Ultrasonographic imaging of the hand and wrist in rheumatoid arthritis

Lund, Pamela J.; Heikal, A; Maricic, Michael; Krupiński, Elizabeth A.; Williams, Craig D.

doi:10.1007/bf00204858

Cited by 68 publications

(24 citation statements)

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“…The selected papers were then divided among the group members and assessed according to an agreed scoring sheet (for results of Evaluation score, see Table 1) 4,5,[8][9][10][11][12][13][14][15][16][17][18][19][20][21][22][23][24][25][26][27][28][29][30][31][32][33][34][35][36][37][38][39][40][41][42][43][44][45][46][47][48][49][50][51][52][53][54][55]…”

Section: Resultsmentioning

confidence: 99%

Summary Findings of a Systematic Literature Review of the Ultrasound Assessment of Bone Erosions in Rheumatoid Arthritis

et al. 2015

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Section: Resultsmentioning

confidence: 99%

Summary Findings of a Systematic Literature Review of the Ultrasound Assessment of Bone Erosions in Rheumatoid Arthritis

et al. 2015

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“…An erosion was defined as a break in the cortex visible in both transverse and longitudinal planes measuring 2 mm or more [24]. A graded scale was used in which an absence of erosions scored 0, 1-2 erosions scored 1, more than two erosions scored 2 and any large erosions (areas of regional bone destruction) scored 3 [24].…”

Section: Us Scoresmentioning

confidence: 99%

A comparison of clinical vs ultrasound determined synovitis in rheumatoid arthritis utilizing gray-scale, power Doppler and the intravenous microbubble contrast agent 'Sono-Vue'(R)

et al. 2007

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Objectives. Synovitis in rheumatoid arthritis (RA) is assessed clinically by the presence of joint tenderness and swelling. Synovial thickening and increased vascularity may also be detected by high-resolution ultrasonography (US) and power Doppler (PD). This study investigated the relationship between clinical and sonographic features of synovial disease utilizing US, PD and the contrast agent Sono-Vue Õ . Methods. Forty RA patients were recruited. One proximal inter-phalangeal or metacarpophalangeal joint was selected per patient, as being unambiguously either: swollen and tender, just swollen, just tender or neither swollen nor tender (Nil). Ten joints were selected per clinical group. On US, the mean synovial thickness was measured and synovial hypertrophy and erosions were graded subjectively. Synovial vascularity demonstrated by PD was scored subjectively pre-and post-contrast. Results. All grades of synovial vascularity were found in each clinical group including the Nil group. There were significant differences between the four clinical groups for both synovial hypertrophy (P ¼ 0.024) and PD scores pre-(P ¼ 0.022) and post-(P ¼ 0.039) contrast. Tender-only joints showed significantly less vascularity than other groups. Post-contrast, the median PD scores increased in all but the Nil group, in some cases from the normal to abnormal range. Conclusion. Synovitis demonstrated by US and PD is not predicted by patterns of disease as described by joint swelling and tenderness despite unambiguous selection of joints. Synovial vascularity was the least in tender-only joints and was heterogeneous in all other groups, including Nil joints. These findings question the reliability of traditional clinical signs in RA synovitis assessment.

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“…of synovial thickness (with high-frequency 20-MHz transducers) and vascularization (power Doppler US), and early detection of erosions (87)(88)(89). A metaanalysis of 21 studies including 913 patients with RA showed that US was more effective than radiography in the detection of erosions (odds ratio, 0.30; P , .00001), and its efficacy was comparable to that of MR imaging (90).…”

Section: Sodium Imagingmentioning

confidence: 99%

The Role ofRadiologyin the Evolution of the Understanding of Articular Disease

Huang

Schweitzer²

2014

Radiology

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Both the clinical practice of radiology and the journal Radiology have had an enormous effect on our understanding of articular disease. Early descriptions of osteoarthritis (OA) appeared in Radiology. More recently, advanced physiologic magnetic resonance (MR) techniques have furthered our understanding of the early prestructural changes in patients with OA. Sodium imaging, delayed gadolinium-enhanced MR imaging of cartilage, and spin-lattice relaxation in the rotating frame (or T1ρ) sequences have advanced understanding of the pathophysiology and pathoanatomy of OA. Many pioneering articles on rheumatoid arthritis (RA) also have been published in Radiology. In the intervening decades, our understanding of the natural history of RA has been altered by these articles. Many of the first descriptions of crystalline arthropathies, including gout, calcium pyrophosphate deposition, and hydroxyapatite deposition disease, appeared in Radiology.

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Ultrasonographic imaging of the hand and wrist in rheumatoid arthritis

Abstract: Ultrasound can detect abnormalities of the hand and wrist in patients with rheumatoid arthritis compared to normal volunteers. Normal articular anatomy is well demonstrated ultrasonically.

Cited by 68 publications

References 17 publications

Summary Findings of a Systematic Literature Review of the Ultrasound Assessment of Bone Erosions in Rheumatoid Arthritis

Summary Findings of a Systematic Literature Review of the Ultrasound Assessment of Bone Erosions in Rheumatoid Arthritis

A comparison of clinical vs ultrasound determined synovitis in rheumatoid arthritis utilizing gray-scale, power Doppler and the intravenous microbubble contrast agent 'Sono-Vue'(R)

The Role ofRadiologyin the Evolution of the Understanding of Articular Disease

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