Ultrasound anatomy of the normal stifle in the sheep

Kayser, François; Hontoir, Fanny; Clegg, Peter; Kirschvink, Nathalie; Dugdale, Alex; Vandeweerd, Jean Michel

doi:10.1111/ahe.12414

Cited by 4 publications

(2 citation statements)

References 39 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The sheep knee joint is often used as a model in orthopedic research. Kayser et al provided ultrasound images of the sheep knee joint that were relevant in musculoskeletal research ( Kayser et al, 2019 ). The biomechanical characteristics of the patellar tendon, such as elasticity and stiffness, are of paramount importance and constitute major outcome measures in research.…”

Section: Introductionmentioning

confidence: 99%

Large animal models for the study of tendinopathy

Zhang

Zhou

et al. 2022

Front. Cell Dev. Biol.

View full text Add to dashboard Cite

Tendinopathy has a high incidence in athletes and the aging population. It can cause pain and movement disorders, and is one of the most difficult problems in orthopedics. Animal models of tendinopathy provide potentially efficient and effective means to develop understanding of human tendinopathy and its underlying pathological mechanisms and treatments. The selection of preclinical models is essential to ensure the successful translation of effective and innovative treatments into clinical practice. Large animals can be used in both micro- and macro-level research owing to their similarity to humans in size, structure, and function. This article reviews the application of large animal models in tendinopathy regarding injuries to four tendons: rotator cuff, patellar ligament, Achilles tendon, and flexor tendon. The advantages and disadvantages of studying tendinopathy with large animal models are summarized. It is hoped that, with further development of animal models of tendinopathy, new strategies for the prevention and treatment of tendinopathy in humans will be developed.

show abstract

Section: Introductionmentioning

confidence: 99%

Large animal models for the study of tendinopathy

Zhang

Zhou

et al. 2022

Front. Cell Dev. Biol.

View full text Add to dashboard Cite

show abstract

“… 2012 ). Ultrasonographic, CT and MRI anatomy of the stifle have been described (Vandeweerd et al 2012 ; Vandeweerd et al 2013 ; Kayser et al 2019 ).…”

Section: Introductionmentioning

confidence: 99%

Ex vivo study correlating the stiffness of the ovine patellar tendon to age and weight

Kayser

Bori

Fourny

et al. 2022

International Biomechanics

Self Cite

View full text Add to dashboard Cite

Tendons play a crucial role in the musculoskeletal system. In humans, tendon injuries, especially chronic tendinopathy, are very common and the patellar tendon is a frequent location for tendinopathy or injuries. The biomechanical characteristics of the patellar tendon, such as elasticity and stiffness, are of paramount importance and constitute major outcome measures in research studies. We aimed to assess whether the stiffness of the healthy ovine patellar tendon changes with age and weight in a population of normal animals. Sixty-eight ‘patella-patellar tendon-tibial tuberosity’ units from thirty-four Ile-de-France ewes of body mass 65 to 95 kg, euthanized for reasons other than musculoskeletal diseases, underwent a tensile test providing a measure of the tendon stiffness. Animals were sorted into three categories of age (1–2 yo, 3–5 yo, 6–10 yo). We found a positive but not significant correlation between age category and stiffness (r = 0.22, p = 0.27). There was a significantly positive correlation between weight and stiffness (r = 0.39, p = 0.04). In conclusion, the study characterized biomechanical properties of healthy tendons, provided useful reference values, and established the basis for future biomechanical tests on healing tendons in sheep. The most appropriate sheep population for those future studies would be non-overweight young adults presenting with no lameness.

show abstract

Ultrasound assessment of sheep stifle joint undergone lipopolysaccharide-induced synovitis

et al. 2022

View full text Add to dashboard Cite

Synovitis can be induced in animals through the application of bacterial wall lipopolysaccharide and has similar signs to naturally-occurring synovitis. Several studies have been using the sheep species as an experimental model to understand osteoarticular diseases of the femorotibiopatellar (FTP) joint in humans. There are echographic studies on the standardization of normality of the femorotibiopatellar joint in sheep. However, there is a gap in the literature for changes such as acute synovitis. The objective was to serially describe the sonographic aspects of the synovitis process induced by intra-articular infiltration of Escherichia coli (E. coli) lipopolysaccharide in the femorotibiopatellar joint of sheep. Twelve healthy crossbred sheep (Santa Inês x Dorper) were used. Induction of synovitis was performed only in the right FTP joints, which were serially evaluated using ultrasound examination at baseline moment (M0) and 12 (M12), 24 (M24), 48 (M48), 72 (M72), and 120 (M120) hours after lipopolysaccharide infiltration for synovitis induction. Intra-articular application of E. coli lipopolysaccharide resulted in one or more echographic signs of synovitis (increased synovial fluid volume, folding of the synovial membrane, and cellularity in the joint cavity), which were identified early, 12 hours after inoculation, and regressed over the evaluated times (p=0.0001) until disappearing after 120 hours of inoculation.

show abstract

Ultrasound anatomy of the normal stifle in the sheep

Cited by 4 publications

References 39 publications

Large animal models for the study of tendinopathy

Large animal models for the study of tendinopathy

Ex vivo study correlating the stiffness of the ovine patellar tendon to age and weight

Ultrasound assessment of sheep stifle joint undergone lipopolysaccharide-induced synovitis

Contact Info

Product

Resources

About