Ultrasound-assisted extraction of antioxidant phenolic compounds from Lavandula angustifolia flowers using natural deep eutectic solvents: An experimental design approach

Alaşalvar, Hamza; Yıldırım, Zeliha

doi:10.1016/j.scp.2021.100492

Cited by 42 publications

(20 citation statements)

References 47 publications

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“…In other studies, methanolic extracts of L. angustifolia were found to contain a large variety of phenolic acids (vanillic acid, chlorogenic acid, syringic acid, o-coumaric acid, methoxy-cinnamic acid, ferulic acid, 4-hydroxybenzoic, p-coumaric acid and sinapic acid) (Blažeković et al 2010, Spiridon et al 2011, Sytar et al 2016. In their study, Alasalvar and Yildirim (2021) identified gallic acid (1.05 ± 0.61 mg/g), ferulic acid (0.48 ± 0.27 mg/g), caffeic acid (0.19 ± 0.02 mg/g), rosmarinic acid (5.49 ± 0.96 mg/g), and rutin (11.13 ± 0.97 mg/g) using HPLC-DAD in L. angustifolia samples obtained under optimized conditions. In another study, Radulescu et al (2017) analyzed the extracts from flowers of L.…”

Section: Resultsmentioning

confidence: 94%

Analysis of phenolic compounds in flowers and leaves of English Lavender (Lavandula angustifolia Mill.) using UPLC-ESI-MS/MS

Özderin

2022

Artvin Çoruh Üniversitesi Orman Fakültesi Dergisi

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Lavender (Lavandula angustifolia Mill.) is used as raw material in various industries such as pharmaceuticals, cosmetics, etc. This study aims to analyze the phenolic compounds and proportions of medicinal lavender (Lavandula angustifolia) in its leaves and flowers and determine the levels of these compounds. A total of 9 phenolic compounds were identified in the leaf and flower samples obtained from the lavenders grown in Ula (Mugla) during the flowering period. Major phenolic compounds detected in leaf and flower samples of Lavender (Lavandula angustifolia Mill.) during the flowering period were protocatechuic acid (189.38 μg/kg), 3,4-dihydroxybenzaldehyde (168.97 μg/kg), and 4-vanillic acid (77.54 μg/kg).

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Section: Resultsmentioning

confidence: 94%

Analysis of phenolic compounds in flowers and leaves of English Lavender (Lavandula angustifolia Mill.) using UPLC-ESI-MS/MS

Özderin

2022

Artvin Çoruh Üniversitesi Orman Fakültesi Dergisi

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“…To save energy and reduce ultrasonication time, the factor range of ultrasonication time in the RSM experiment was set to 5–15 min. It was also observed that ultrasonic treatment led to a slight increase in the temperature of NADES, which was conducive to reducing the viscosity of NADES and improving the mass-transfer rate in the extraction process [ 27 , 28 , 29 ].…”

Section: Resultsmentioning

confidence: 99%

Ultrasound-Assisted Natural Deep Eutectic Solvent Extraction and Bioactivities of Flavonoids in Ampelopsis grossedentata Leaves

Zhen

Chen

Geng

et al. 2022

Foods

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We performed ultrasound-assisted extraction coupled with natural deep eutectic solvents (NADES) to achieve the green and efficient preparation of flavonoid extract from Ampelopsis grossedentata leaves. We then evaluated its antioxidant and antiproliferative activities. A NADES consisting of choline chloride and glucose at a molar ratio of 4:1 with 20% water was determined to be the most suitable solvent. The optimal extraction conditions were: a liquid-to-solid ratio of 30 mL/g, an ultrasonication power of 490 W, and an ultrasonication time of 6.5 min. The actual flavonoid yield was 83.93%, which was close to the predicted yield. Further, 86.75% of the flavonoids were recovered by adding the same volume of phosphate buffer saline (100 mM, pH of 7.0) to the extract solution. Although the chemical antioxidant activities of the flavonoid extract were slightly inferior to those of dihydromyricetin, the flavonoid extract could still effectively inhibit the proliferation of human breast MDA-MB-231 cells by inducing cell apoptosis, retarding the cell cycle, changing the mitochondrial membrane potential and scavenging intracellular reactive oxygen species (ROS). The obtained results can provide a reference in the development of plant-derived functional foods.

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“…[17] Cyanus segetum Hill Rosmarinic acid Lavandula angustifolia Mill. [48] Four phenolic acids (gallic acid-1.05 ± 0.61 (mg/g); caffeic acid-0.19 ± 0.02 (mg/g); ferulic acid-0.48 ± 0.27 (mg/g); rosmarinic acid-5.49 ± 0.96 (mg/g)) were also identified in the flower extract of Lavandula angustifolia Mill., by ultrasound-assisted extraction with natural eutectic solvents (NADESs) and reference solvents (70% ethanol, 80% methanol) [48]. Krzymi ńska et al [49], studied the phenolic acid profile of five cultivars of Tulipa gesneriana L., in which significant amounts of hydroxybenzoic acids (phydroxybenzoic, 2,5-dihydroxybenzoic, gallic, vanillic, syringic, salicylic, protocatechuic), and hydroxycinnamic acids (trans-cinnamic, p-coumaric, caffeic, ferulic, chlorogenic, sinapic) were identified, while it was noted that the profile of the phenolic acids of the flowers studied varied according to the cultivar, the production system, and the storage time.…”

Section: Taraxacum Campylodesmentioning

confidence: 98%

The Compositional Aspects of Edible Flowers as an Emerging Horticultural Product

et al. 2021

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Edible flowers are becoming very popular, as consumers are seeking healthier and more attractive food products that can improve their diet aesthetics and diversify their dietary sources of micronutrients. The great variety of flowers that can be eaten is also associated with high variability in chemical composition, especially in bioactive compounds content that may significantly contribute to human health. The advanced analytical techniques allowed us to reveal the chemical composition of edible flowers and identify new compounds and effects that were not known until recently. Considering the numerous species of edible flowers, the present review aims to categorize the various species depending on their chemical composition and also to present the main groups of compounds that are usually present in the species that are most commonly used for culinary purposes. Moreover, special attention is given to those species that contain potentially toxic or poisonous compounds as their integration in human diets should be carefully considered. In conclusion, the present review provides useful information regarding the chemical composition and the main groups of chemical compounds that are present in the flowers of the most common species.

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Ultrasound-assisted extraction of antioxidant phenolic compounds from Lavandula angustifolia flowers using natural deep eutectic solvents: An experimental design approach

Cited by 42 publications

References 47 publications

Analysis of phenolic compounds in flowers and leaves of English Lavender (Lavandula angustifolia Mill.) using UPLC-ESI-MS/MS

Analysis of phenolic compounds in flowers and leaves of English Lavender (Lavandula angustifolia Mill.) using UPLC-ESI-MS/MS

Ultrasound-Assisted Natural Deep Eutectic Solvent Extraction and Bioactivities of Flavonoids in Ampelopsis grossedentata Leaves

The Compositional Aspects of Edible Flowers as an Emerging Horticultural Product

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