Ultrasound-assisted extraction, optimization, and purification of total flavonoids from <mml:math xmlns:mml="http://www.w3.org/1998/Math/MathML" altimg="si10.svg"><mml:mrow><mml:mi mathvariant="italic">Daphne</mml:mi><mml:mspace width="0.35em"/><mml:mi mathvariant="italic">genkwa</mml:mi></mml:mrow></mml:math> and analysis of their antioxidant, anti-inflammatory, and analgesic activities

Xiang, Yi; Liu, Zheng; Liu, Yanzhi; Dong, Bin; Yang, Changqing; Li, Hanhan

doi:10.1016/j.ultsonch.2024.107079

Ultrasonics Sonochemistry

2024

DOI: 10.1016/j.ultsonch.2024.107079

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Ultrasound-assisted extraction, optimization, and purification of total flavonoids from Daphnegenkwa and analysis of their antioxidant, anti-inflammatory, and analgesic activities

Yi Xiang,

Zheng Liu,

Yanzhi Liu

et al.

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Enrichment, Antioxidant and Enzyme Inhibition Activities of Flavonoids from Artemisia Selengensis Turcz.

Wang,

Shi

et al. 2024

Chemistry & Biodiversity

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Macroporous resin was used to enrich flavonoids in the ethyl acetate extract of Artemisia Selengensis Turcz. Based on a single factor experiment, the enrichment process was optimized using the response surface method. The optimal parameters of the enrichment process were a sample concentration of 0.3 mg/mL, a loading rate of 1 mL/min, an elution flow rate of 2 mL/min, and a total flavonoid content of 155.38 ± 0.97 mg/g. The flavonoids enriched by AB‐8 macroporous resin demonstrated significant scavenging activities against DPPH, ABTS+, and hydroxyl free radicals, and also exhibited certain inhibitory effects on α‐amylase and α‐glucosidase. Among them, the scavenging ability of the flavonoids enriched by AB‐8 macroporous resin on hydroxyl free radical (IC50 = 30.31 ± 1.92 μg/mL) was the closest to Vc, and the inhibitory effect on α‐glucosidase (IC50 = 16.19 ± 1.35 μg/mL) was the best. These findings confirmed the potential of Artemisia Selengensis Turcz. is a natural antioxidant and hypoglycemic drug.

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Enrichment, Antioxidant and Enzyme Inhibition Activities of Flavonoids from Artemisia Selengensis Turcz.

Wang,

Shi

et al. 2024

Chemistry & Biodiversity

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Study on optimization of extraction and purification processes for total flavonoids from Lycopi herba roots and their anti-proliferative effects on fibrous synoviocytes in human rheumatoid arthritis

Chen,

Jiang,

Liu

et al. 2025

Ultrasonics Sonochemistry

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Ultrasound-assisted extraction, optimization, and purification of total flavonoids from Daphnegenkwa and analysis of their antioxidant, anti-inflammatory, and analgesic activities

Cited by 2 publications

References 58 publications

Enrichment, Antioxidant and Enzyme Inhibition Activities of Flavonoids from Artemisia Selengensis Turcz.

Enrichment, Antioxidant and Enzyme Inhibition Activities of Flavonoids from Artemisia Selengensis Turcz.

Study on optimization of extraction and purification processes for total flavonoids from Lycopi herba roots and their anti-proliferative effects on fibrous synoviocytes in human rheumatoid arthritis

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