Ultrasound Elastography of Breast Lesions in Chinese Women: A Multicenter Study in China

Zhi, Hui; Ou, Bing; Xiao, Xiaoyun; Peng, Yulan; Wang, Yi; Li, Lisha; Xiao, Ying; Liu, Shoujun; Wu, Changjun; Jiang, Yuxin; Parajuly, Shyam Sundar; Xu, Ping; Hao, Yi; Li, Jing; Luo, Baoming

doi:10.1016/j.clbc.2013.02.015

Cited by 43 publications

(30 citation statements)

References 22 publications

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“…US imaging systems specially equipped with elastography features such as VTI allow the investigation of elastic tissue properties on the basis of UE. Our results for specificity, sensitivity, and accuracy of UE were 75.6, 80.8, and 77.9%, respectively, much lower (except for sensitivity) than those reported by Zhi et al [2] (86.4, 80.8, and 83.5%) and Xue et al [5] (85.1, 93.6, and 89.7%). Both the specificity and accuracy of UE were lower than those of US in our study, which is in contrast to the findings of Zhi et al [2] and Xue et al [5] according to which the specificity and accuracy of UE were higher than those of US.…”

Section: Discussioncontrasting

confidence: 82%

“…The histopathologic nature of a breast lesion may be revealed by measuring its elasticity [1][2][3][4]. US imaging systems specially equipped with elastography features such as VTI allow the investigation of elastic tissue properties on the basis of UE.…”

Section: Discussionmentioning

confidence: 99%

“…The breast lesions were assessed according to BI-RADS based on US first, and the 5-point scoring system for UE second. The UE characteristics were analyzed with reference to the 5-point scoring system proposed by Zhi et al [2]: A score of 1 indicated even strain for the entire lesion (i.e., the entire lesion was evenly shaded in green); a score of 2 indicated strain in the majority of the lesion with focal no-strain spots (i.e., the lesion was shaded in green with focal blue spots); a score of 3 indicated strain and no strain in half of the lesion each (i.e., the lesion was half green and half blue); a score of 4 indicated no or little strain in the entire lesion (i.e., the entire lesion was blue or predominantly blue with a little green); and a score of 5 indicated no or little strain in the entire lesion and the surrounding area (i.e., the entire lesion and its surrounding area were blue or blue with focal green spots). An analysis on a per lesion basis was performed.…”

Section: Image Analysismentioning

confidence: 99%

“…Ultrasound elastography (UE), which can examine tissue elasticity/ hardness, is used for the evaluation of breast diseases with a focus on the differentiation between benign and malignant breast lesions, based upon the clinical finding that malignant lesions of the breast are generally harder on palpation than normal breast tissue and benign lesions [1][2][3][4][5][6][7][8][9]. Published reports have shown that UE combined with US can reduce benign biopsies [1,3].…”

Section: Introductionmentioning

confidence: 99%

“…Published reports have shown that UE combined with US can reduce benign biopsies [1,3]. However, reports of the advantages and pitfalls of UE in the assessment of breast lesions have been discrepant [2,[6][7][8]. Therefore, summarization of experiences and further investigation of the role of UE in the assessment of breast lesions is necessary.…”

Section: Introductionmentioning

confidence: 99%

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Combining Virtual Touch Tissue Imaging and BI-RADS May Improve Solid Breast Lesion Evaluation

Cui

Huang

et al. 2017

Breast Care

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Background: Ultrasound elastography (UE) is a novel imaging method. The purpose of this study was to determine the utility of Virtual Touch tissue imaging in the evaluation of solid breast lesions. Patients and Methods: 209 breast solid lesions in 192 patients that had been evaluated using ultrasound (US) and UE were reviewed and analyzed. Results: The sensitivity, specificity, accuracy, positive predictive value, and negative predictive value for UE, US, and US plus UE in the differentiation of malignant from benign breast lesions were 80.8, 75.6, 77.9, 73.1, and 82.8% for UE, 87.2, 86.1, 86.6, 83.7, and 89.2% for US, and 92.5, 86.9, 89.5, 85.3, and 93.4% for US plus UE. There were significant differences between UE and US plus UE (all p < 0.05). Except for accuracy, there were no significant differences between UE and US or US and US plus UE (all p > 0.05). The area under the curve obtained from the ROC curve for UE, US, and US plus UE in differentiating malignant from benign lesions was 0.845, 0.884, and 0.922, respectively. Conclusion: The UE scoring system is not superior to BI-RADS in the sonographic evaluation of solid breast lesions. Combined use may improve the performance.

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