“…Among the various abnormalities within the carpal tunnel reported, the increase of the cross-sectional area (CSA) of the median nerve is the most commonly studied ultrasound abnormality 3. Additionally, ultrasound allows the identification of secondary causes of CTS, such as synovitis, tenosynovitis, calcified masses or tophaceous gout, as pointed out by zhu et al 4 We acknowledge that the diagnostic value of ultrasound is not perfect, as some patients may suffer from CTS despite a normal ultrasound result and, vice versa, abnormal ultrasound findings do not necessarily indicate CTS 1. In these cases, additional tests, such as nerve conduction studies (although the sensitivity and specificity of this method are far away from 100% as shown in our and several other studies) are required to establish the final diagnosis 1 5…”