A two-day-old heifer calf presented with a non-weight bearing right hindlimb lameness following a traumatic event. A closed, complete, overriding, displaced fracture of the distal right metatarsal diaphysis was diagnosed and closed reduction and cast placement was elected as treatment. The calf was sedated intravenously with a combination of diazepam and ketamine. With the calf in lateral recumbency, sciatic and femoral nerve blocks were performed using procaine to provide analgesia and muscle relaxation for the procedure. The procedure was performed with the patient sedated and no further anaesthetics or analgesics were needed. This report is the first describing the use of sciatic and femoral nerve blocks as analgesia for a young calf. The success of the technique allowed a decrease in the dosage of other systemic drugs. This is an important factor in decreasing potential complications related to anaesthesia in these patients.