Ultrasound Guided Fine-Needle Aspiration Biopsy of Thyroid Nodules: Does Radiologist Assistance Decrease the Rate of Unsatisfactory Biopsies?

Kaliszewski, Krzysztof; Zubkiewicz‐Kucharska, Agnieszka; Wojtczak, Beata; Strutyńska−Karpińska, Marta; Zaleska-Dorobisz, Urszula; Leśków, Elżbieta

doi:10.17219/acem/60084

Cited by 9 publications

(7 citation statements)

References 30 publications

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“… 10 UG-FNAB is the most cost-effective procedure that provides useful diagnostic information relating to further clinical management. 11 The clinical and practical purpose of this diagnostic tool is to reduce the number of unnecessary “diagnostic” surgical procedures in patients with benign nodules and detects those individuals in whom the risk of malignancy is high.…”

Section: Discussionmentioning

confidence: 99%

Evaluation of selected ultrasound features of thyroid nodules with atypia of undetermined significance/follicular lesion of undetermined significance for the Bethesda reporting system for thyroid cytology

Kaliszewski¹,

Diakowska²,

Wojtczak³

et al. 2018

CMAR

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Background and objectiveThe risk of malignancy from “atypia of undetermined significance/follicular lesion of undetermined significance” (AUS/FLUS) is estimated to lie between 5% and 15%; however, some authors suggest that the risk of malignancy in AUS/FLUS depends upon specific clinical situations. This was a retrospective study which aimed to determine the incidence and risk of thyroid cancer (TC) based upon selected ultrasound features from patients with thyroid nodules (TN) classified as AUS/FLUS.MethodsUnivariate and multivariate logistic regression analyses were used to identify significant associations between ultrasound features and the risk of TC.ResultsOf 127 patients with TN classified as AUS/FLUS who underwent thyroidectomy, 114 (89.8%) had benign disease while 13 (10.2%) had TC. Univariate analysis identified several significant predictors for TC (all p<0.05), including microcalcifications, hypoechogenicity, the prevalence of irregular margins, a taller rather than a wide form, high vascularity, and fast tumor growth. Multivariate analysis further showed that microcalcifications (odds ratio =21.37; p=0.024) and fast growth (odds ratio =22.70; p=0.021) were significant and independent factors associated with the risk of developing TC.ConclusionMicrocalcifications and fast growth of the TN could therefore be used as predictive factors for the development of TC in patients with AUS/FLUS.

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Section: Discussionmentioning

confidence: 99%

Evaluation of selected ultrasound features of thyroid nodules with atypia of undetermined significance/follicular lesion of undetermined significance for the Bethesda reporting system for thyroid cytology

Kaliszewski¹,

Diakowska²,

Wojtczak³

et al. 2018

CMAR

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“…With the improved resolution of high frequency ultrasound and new technologies, the detection rate of thyroid nodules has improved significantly, but it is still necessary to use ultrasound-guided fine-needle aspiration biopsy (US-FNAB) to determine the nature of thyroid nodules (Singh Ospina et al 2016 ; Kaliszewski et al 2016 ). US-FNAB has many advantages, such as real-time guidance, simple operation, safe, few contraindications and complications, and an effective method to identify the benign and malignant thyroid nodules (Cooper et al 2009 ; Moon et al 2012 ; Kim et al 2009a , b ; Lee et al 2011 ).…”

Section: Introductionmentioning

confidence: 99%

Fine needle aspiration cytology guided by ultrasound in the diagnosis of subcentimetre thyroid nodules

et al. 2016

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BackgroundThis study aimed to investigate the value of fine needle aspiration biopsy (FNAB) under ultrasound guidance in diagnosis of thyroid nodules. In a retrospective analysis of FNAB in 1050 cases of patients with 1100 nodules, patients were divided according to the maximum diameter of their nodules into two groups: >1.0 and ≤1.0 cm. The ultrasound-guided FNAB cytology results were compared between two groups.ResultsUltrasound findings showed that among 1100 thyroid nodules, 547 were highly suspicious, 358 were moderately, 175 were low, and 19 were very low. Cytology results showed papillary carcinomas in 453, possible papillary cancer in 126 cases, follicular tumors in 26, suspicious follicular tumors in 6, atypical cells in 7, nodular goiter in 289, colloid in 13, chronic lymphocytic thyroiditis in 175, and undiagnosed specimen in 5. Ultrasound diagnosis of thyroid nodules had an overall sensitivity of 86.0 %, and a specificity of 81.9 %. In nodules larger than 1.0 cm, the sensitivity was 92.8 %, and the specificity 92.3 %. In nodules ≤1.0 cm, the sensitivity was 82.4 %, and the specificity was 81.7 %.ConclusionsPatients with highly suspicious thyroid nodules on ultrasonography, regardless of nodule sizes, should receive ultrasound-guided FNAB to confirm their natures and direct clinical managements.

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“…There is disagreement in the literature regarding the optimal technique for performing thyroid FNAs (11,16,17,(22)(23)(24)(25)(26).…”

Section: Discussionmentioning

confidence: 99%

Standardization of thyroid fine needle aspiration procedure and outcomes within an endocrine surgery department

et al. 2021

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Background: Fine needle aspiration (FNA) biopsy is an essential procedure for thyroid nodules. Although, the efficacy of surgeon-performed thyroid FNA biopsies has been demonstrated in the literature, there are insufficient data regarding how to establish an efficient program with a low insufficiency rate within a group practice.Methods: An endocrine surgery thyroid FNA biopsy program was established in 2000 by one surgeon, with training of additional partners during fellowship and upon recruitment. The results within 18 years were analyzed. The FNA biopsies were performed by endocrine surgeons under ultrasound guidance without onsite pathologist review.Results: A total of 5,469 FNA biopsies were performed by 7 surgeons. The total number of FNA biopsies performed by each surgeon varied between 291-1,378. FNA biopsies were performed in 2 passes using 22-gauge needles under constant suction. The overall insufficiency rate was 4.3%, with individual surgeon rates ranging between 2.7% and 7.2%. The insufficiency rate for the whole team ranged between 3.3% and 5% when examined in 5-year blocks.Conclusions: This study shows that an establishment of a highly efficient thyroid FNA biopsy program within a group practice is possible with a structured endocrine surgical training and adoption of a standard technique.

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Ultrasound Guided Fine-Needle Aspiration Biopsy of Thyroid Nodules: Does Radiologist Assistance Decrease the Rate of Unsatisfactory Biopsies?

Cited by 9 publications

References 30 publications

Evaluation of selected ultrasound features of thyroid nodules with atypia of undetermined significance/follicular lesion of undetermined significance for the Bethesda reporting system for thyroid cytology

Evaluation of selected ultrasound features of thyroid nodules with atypia of undetermined significance/follicular lesion of undetermined significance for the Bethesda reporting system for thyroid cytology

Fine needle aspiration cytology guided by ultrasound in the diagnosis of subcentimetre thyroid nodules

Standardization of thyroid fine needle aspiration procedure and outcomes within an endocrine surgery department

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