Ultrasound-Guided Foam Sclerotherapy for Treating Incompetent Great Saphenous Veins—Results of 5 Years of Analysis and Morphologic Evolvement Study

Chen, Chien‐Hsun; Chiu, Chih‐Yung; Yang, Chih‐Hsun

doi:10.1111/j.1524-4725.2012.02408.x

Cited by 28 publications

(14 citation statements)

References 26 publications

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“…After full text evaluation, 62 studies discussing sclerotherapy management of varicose veins were included involving 3689 patients (CDFS 789 and FS 2900). 11,16,19,20,28–84 Of these, there were 48 studies for UGFS and 15 studies for CDFS. There was only one randomized controlled trial directly comparing these two alternatives.…”

Section: Resultsmentioning

confidence: 99%

Catheter-directed foam sclerotherapy, an alternative to ultrasound-guided foam sclerotherapy for varicose vein treatment: A systematic review and meta-analysis

et al. 2020

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Purpose Catheter-directed foam sclerotherapy is a new addition to the treatment modalities available for varicose veins. As a modification of ultrasound-guided foam sclerotherapy, catheter-directed foam sclerotherapy has been purported to offer higher complete ablation rates and an improved safety profile. The aim of this study is to appraise the current literature on the outcomes of catheter-directed foam sclerotherapy compared to ultrasound-guided foam sclerotherapy in chronic venous insufficiency. Methods The review of the literature was conducted using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses guidelines. Data from studies that reported the outcomes of catheter-directed foam sclerotherapy and ultrasound-guided foam sclerotherapy were extracted, to determine the pooled proportion of complete ablation rates, using a random effect meta-analysis model. Results A total of 62 studies, involving 3689 patients, were included in the systematic review. Higher rates of complete ablation were reported in catheter-directed foam sclerotherapy compared to ultrasound-guided foam sclerotherapy during the short- and medium-term follow-ups (Relative Risk = 1.06, Relative Risk = 1.15, Relative Risk = 1.19, p < 0.05). Fewer major and minor complications were also reported in patients who underwent catheter-directed foam sclerotherapy (Relative Risk = 0.23, Relative Risk= 0.43–0.76, p < 0.05). Conclusion Catheter-directed foam sclerotherapy has been demonstrated to have many advantages over ultrasound-guided foam sclerotherapy, offering superior complete ablation rates in the short-, medium- and long-term follow-ups. It also has a better safety profile, conferring a lower risk of major and minor complications. The conclusions should however be viewed in the context of significant limitations imposed by limited study data.

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Section: Resultsmentioning

confidence: 99%

Catheter-directed foam sclerotherapy, an alternative to ultrasound-guided foam sclerotherapy for varicose vein treatment: A systematic review and meta-analysis

et al. 2020

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“…As agents and techniques settle into common use, a new scope of research is necessary to examine what can be expected of them in the long term. This study by Chih‐Hsun Yang and colleagues is a significant addition to this new scope of research . This was a well‐designed study that was reported thoroughly yet concisely.…”

mentioning

confidence: 90%

“…This study by Chih-Hsun Yang and colleagues is a significant addition to this new scope of research. 1 This was a well-designed study that was reported thoroughly yet concisely.…”

mentioning

confidence: 99%

Commentary for “Ultrasound Guided Foam Therapy for Treating Incompetent Great Saphenous Veins: Results of 3-Year Analysis and Morphologic Evolvement Study”

Raymond‐Martimbeau

2012

Dermatologic Surgery

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“…Sclerotherapy of the varicose veins of the lower limbs is a medical procedure that consists of damaging the blood wall (endothelium but also some other surrounding structures) by injecting a certain chemical solution (6,7). This leads to the sclerosis of the blood vessel, following the destruction of the endothelium.…”

Section: Introductionmentioning

confidence: 99%

Comparative study in leg telangiectasias treatment with Nd:YAG laser and sclerotherapy

et al. 2018

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Telangiectasias and reticular veins of the lower extremities are common lesions. Sclerotherapy is considered the gold standard for treatment. The aim of our prospective randomized study was to compare the efficacy and safety of hypertonic 20% saline/2% lignocaine (HS) versus polidocanol 0.5% (POL) versus long-pulsed neodymium:ytrium aluminium garnet (Nd:YAG) laser (LAS) treatments of leg telangiectasias in women, using each patient as her own control. We included in this study 285 women with primary leg telangiectasias and reticular veins (C 1A E p A S1 P N) in order to be treated with sclerotherapy or laser. One leg was treated with either LAS, POL or HS. The other leg received, randomly, one other of these treatments. At the end there were 190 legs treated with each method. There were two sessions at 8-week interval. Assessment of vessel clearing and complications was conducted 2 months after each session using before and after photographs of the leg vessels using a six-point scale from 0 (no change) to 5 (100% cleared). For telangiectasias under 1 mm diameter LAS was better (RR=9.72, P<0.0001) than HS and also POL was better (RR=2.70, P=0.003); for telangiectasias over 1 mm diameter LAS and POL were better too (RR=2.70, P=0.003) respectively (RR=1.44, P=0.00756). For telangiectasias under 1 mm LAS treatment is clearly superior to POL treatment. For telangiectasias over 1 mm the hazard regression model showed a hazard ratio of 3.97 (P=0.047) for LAS and 4.96 (P=0.486) for POL vs. HS treatment. In conclusion, telangiectasias and reticular veins of the lower extremities can be successfully treated with Nd:YAG laser or sclerotherapy. Nd:YAG laser is recommended in treating small telangiectasias (under 1 mm diameter) while sclerotherapy with polidocanol is more efficient as long as telangiectasias diameter is growing.

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Ultrasound-Guided Foam Sclerotherapy for Treating Incompetent Great Saphenous Veins—Results of 5 Years of Analysis and Morphologic Evolvement Study

Abstract: UGFS is effective in sealing incompetent GSV segments. It is a minimally invasive procedure and can be redone several times in cases of recurrence. UGFS is simpler and less painful than stripping surgery and endovenous laser treatment.

Cited by 28 publications

References 26 publications

Catheter-directed foam sclerotherapy, an alternative to ultrasound-guided foam sclerotherapy for varicose vein treatment: A systematic review and meta-analysis

Catheter-directed foam sclerotherapy, an alternative to ultrasound-guided foam sclerotherapy for varicose vein treatment: A systematic review and meta-analysis

Commentary for “Ultrasound Guided Foam Therapy for Treating Incompetent Great Saphenous Veins: Results of 3-Year Analysis and Morphologic Evolvement Study”

Comparative study in leg telangiectasias treatment with Nd:YAG laser and sclerotherapy

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