Ultrasound-guided laser ablation versus surgery for solitary papillary thyroid microcarcinoma: a retrospective study

Zhou, Wei; Ni, Xiaofeng; Xu, Shumao; Zhang, Lu; Chen, Yudong; Zhan, Wei

doi:10.1080/02656736.2019.1649475

Cited by 47 publications

(51 citation statements)

References 35 publications

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“…Besides, compared with routine surgery methods (total thyroidectomy and lobectomy), the incidence rate of complications and recurrence of MWA techniques were not statistically significant, whereas the operative time, blood loss, length of hospital stay, hospital cost (RMB) were significantly decreased (Table 2). 12,18,31,51 Notably, compared with the surgery group, PTMC patients who underwent RFA had lower scores in "problems with scarring" and "less interest in sex" sections of THYCA-QOL (Thyroid Cancer-Specific Quality of Life Questionnaire. Lower the score is, the better quality of life will be).…”

Section: Comparison With Surgerymentioning

confidence: 99%

“…13,16,17 Besides MWA, other TA techniques including laser ablation (LA), radiofrequency ablation (RFA) were also gradually introduced to the clinical practice and also achieved the same therapeutic effects. [18][19][20][21][22] Noticeably, based on the long-term follow-up of patients who underwent these series of techniques, a significant reduction in primary tumor volume, satisfying tumor resolving, and fewer postoperative complications have been documented, compared with routine surgery. 12,18,23 Therefore, this review intends to summarize the achievements of the past few years in evaluating the efficacy and safety of these TA techniques in dealing with PTMC.…”

Section: Introductionmentioning

confidence: 99%

“…[18][19][20][21][22] Noticeably, based on the long-term follow-up of patients who underwent these series of techniques, a significant reduction in primary tumor volume, satisfying tumor resolving, and fewer postoperative complications have been documented, compared with routine surgery. 12,18,23 Therefore, this review intends to summarize the achievements of the past few years in evaluating the efficacy and safety of these TA techniques in dealing with PTMC. Besides, we also quantitatively analyze the specific assessment indicators after the TA operation, which can provide a more intuitive comparison of differences among them.…”

Section: Introductionmentioning

confidence: 99%

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Thermal Ablation for Papillary Thyroid Microcarcinoma: How Far We Have Come?

Min

Wang

Chen

et al. 2020

CMAR

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Purpose Thermal ablation (TA), as one of the most currently remarkable technologies, has achieved great success in many malignant diseases including but not limited to hepatic and renal carcinoma. In recent years, this technology was gradually introduced to the treatment of papillary thyroid microcarcinoma (PTMC) and even papillary thyroid carcinoma (PTC). Thereby, we summarized the current progress of TA development in the treatment of PTMC. Methods The latest relevant literature from the PubMed database with keywords “thermal ablation”, “papillary thyroid microcarcinoma”, “microwave ablation”, “radio-frequency ablation”, and “laser ablation”, among others, were comprehensively reviewed in this article. The follow-up outcomes of patients in these articles were analyzed. Results The efficacy and safety of TA including microwave ablation (MWA), laser ablation (LA), and radiofrequency ablation (RFA) in the treatment of PTC and PTC have been intensively studied. Based on existing clinical trials, the relatively long-term follow-up (range, from 6 to 64.2 months) results in MWA, LA, and RFA were satisfactory that tumor volume reduction rate (VRR) reached and even surpass 99%. Compared with routine surgery methods (total thyroidectomy and lobectomy), the incidence rate of complications was relatively lower and the recurrence rate of TA techniques was not statistically significant, whereas the operative time, blood loss, length of hospital stay, and hospital cost were significantly decreased. Conclusion TA presents the same satisfactory therapeutic effects but minimal postoperative trauma can significantly improve the patients’ quality of life. However, future larger sample, multicenter, and prospective randomized controlled trials are urgently needed to validate the feasibility of TA in dealing with PTMC.

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Section: Comparison With Surgerymentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Thermal Ablation for Papillary Thyroid Microcarcinoma: How Far We Have Come?

Min

Wang

Chen

et al. 2020

CMAR

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“…No matter which method has more advantages, RFA and LA are all safe and effective measures for their low complication rates, high nodular VRRs and the preservation of thyroid function [35][36][37][38][39] . Zhou et al 40 conducted a retrospective study on solitary papillary thyroid carcinoma (36 received LA and 45 underwent surgery). No signi cant difference was found in the recurrence rates between the LA and surgical group (5.6% vs.…”

Section: Discussionmentioning

confidence: 99%

Radiofrequency Ablation for Benign Thyroid Nodules: Efficacy According to the Types of Thyroid Nodules

Li¹,

Xue²,

Xu³

et al. 2020

Preprint

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Percutaneous radiofrequency ablation (RFA) has been recommended as minimally invasive treatment for patients with symptomatic benign thyroid nodules (BTNs) because of the large number of clinical applications. This retrospective observational study sought to evaluate the clinical outcomes of RFA for BTNs. From 2014 to 2019, a sample size of 1289 patients treated by RFA were 226 ones with solid nodules and 865 ones with cystic-solid nodule, respectively. The efficacy including the nodule maximal diameter reduction ratio (MDRR), the volume reduction ratio (VRR) and the cosmetic scores reduction ratio (CSRR). The results of the nodule MDRR and VRR in the cystic-solid nodule group were significantly better than those in the solid nodule group at the 3rd and 6th month, and the CSRR in the two groups showed statistically significant difference at the 3rd month. In a word, RFA is an effective method for symptomatic benign solid or cystic-solid nodules. The achieved MDRR and VRR in the cystic-solid nodule group were significantly better than those in the solid nodule group at the 3rd and 6th month.

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“…In order to improve the safety and reduce the invasiveness of treatment, US‐guided percutaneous thermal ablations, such as laser ablation (LA), microwave ablation (MWA), and radiofrequency ablation (RFA), have attracted a great deal of interests in minimally invasive treatments of various organs as well as benign thyroid nodules [6–10]. The first application of LA with regard to PTMC [11] was proved to be a safe and effective ablative treatment in several studies [12–14]. In recent years, MWA has also been used to treat solitary PTMC, which showed promising results [15,16].…”

Section: Introductionmentioning

confidence: 99%

Ultrasound‐Guided Laser Ablation Versus Microwave Ablation for Patients With Unifocal Papillary Thyroid Microcarcinoma: A Retrospective Study

Zhou

et al. 2020

Lasers Surg Med

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Background and Objectives: The objective of this study is to compare the efficacy and the safety of ultrasound-guided microwave ablation (MWA) and laser ablation (LA) for the treatment of papillary thyroid microcarcinoma (PTMC). Study Design/Materials and Methods: A total of 67 patients with unifocal PTMC were studied retrospectively, including 33 cases who underwent MWA (MWA group) and 34 cases who received LA (LA group). The follow-up consisted of thyroid function tests, ultrasonography, contrast-enhanced ultrasonography (CEUS), and chest X-ray or computed tomography scan. The treatment response and complications were compared between the two groups. Results: The follow-up time for the MWA and LA group was 23.3 ± 4.4 and 22.8 ± 4.1 months, respectively. All the ablations were successfully performed as planned without complementary ablations, and it was confirmed by CEUS after treatment in both groups. It was observed that, at the last follow-up, the mean largest diameter decreased from 5.0 ± 1.4 mm to 0.1 ± 0.4 mm (MWA group) and from 4.5 ± 1.6 mm to 0.6 ± 1.2 mm(LA group) (P < 0.05 for both). The average volume reduced from 51.9 ± 40.8 to 0.2 ± 1.0 mm 3 (MWA group) and from 38.5 ± 43.0 to 1.3 ± 3.8 mm 3 (LA group) (P < 0.05 for both). The complication rates did not differ between the MWA group (9.1%) and the LA group (2.9%) (P > 0.05). No local recurrence or distant metastasis occurred in either group. Conclusions: During the short-term follow-up period, ultrasound-guided MWA and LA were both safe and effective methods in treating patients with unifocal PTMC. Lasers Surg. Med.

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Ultrasound-guided laser ablation versus surgery for solitary papillary thyroid microcarcinoma: a retrospective study

Cited by 47 publications

References 35 publications

Thermal Ablation for Papillary Thyroid Microcarcinoma: How Far We Have Come?

Thermal Ablation for Papillary Thyroid Microcarcinoma: How Far We Have Come?

Radiofrequency Ablation for Benign Thyroid Nodules: Efficacy According to the Types of Thyroid Nodules

Ultrasound‐Guided Laser Ablation Versus Microwave Ablation for Patients With Unifocal Papillary Thyroid Microcarcinoma: A Retrospective Study

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