Ultrasound-guided perineal laser ablation versus prostatic arterial embolization for benign prostatic hyperplasia: two similar short-term efficacies

Cai, Huai-Jie; Zhu, Conghui; Fang, Jianhua

doi:10.1177/02841851221140214

Cited by 4 publications

(6 citation statements)

References 29 publications

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“…The measured total energy deployed was 6616.2–10,522 J, while two studies reported the coagulation zone, which was 10.3–11.7 ml. 12,19 Operative and perioperative data are summarized in Table 3.…”

Section: Resultsmentioning

confidence: 99%

“…After excluding 74 records (65 due to irrelevant subjects, 3 conference abstracts, and 6 protocols with no published outcomes), 25 full texts were screened for eligibility. Finally, after excluding 3 reviews and 11 studies not on BPH or transperineal route of therapy, 11 studies were deemed eligible for inclusion: 1 RCT, 10 1 animal study, 11 and 9 observational studies, [12][13][14][15][16][17][18][19][20] from which one was comparative. 12 Since only two comparative studies were found, one of which was an RCT and they compared TPLA with either PAE or TURP, no meta-analysis was performed.…”

Section: Study Selectionmentioning

confidence: 99%

“…Finally, after excluding 3 reviews and 11 studies not on BPH or transperineal route of therapy, 11 studies were deemed eligible for inclusion: 1 RCT, 10 1 animal study, 11 and 9 observational studies, [12][13][14][15][16][17][18][19][20] from which one was comparative. 12 Since only two comparative studies were found, one of which was an RCT and they compared TPLA with either PAE or TURP, no meta-analysis was performed. PRISMA flow diagram is shown in Figure 1.…”

Section: Study Selectionmentioning

confidence: 99%

Section: Comparative Studiesmentioning

confidence: 99%

“…Two comparative studies reported the effectiveness and safety of TPLA compared to PAE 12 and TURP. 10 Cai et al 12 found that both treatments led to improvement compared to baseline for functional outcomes, but no significant differences existed between them. Bertolo et al 10 reported that both TURP and TPLA were effective in reducing symptoms and improving objective outcomes postoperatively at 6 months of follow-up, but TURP was superior in terms of Qmax improvement (+14.9 versus +5.4 ml/s, p < 0.001), while statistically nonsignificant differences were found regarding PVR reduction, IPSS, and QoL improvement.…”

Section: Comparative Studiesmentioning

confidence: 99%

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Transperineal laser ablation as a new minimally invasive surgical therapy for benign prostatic hyperplasia: a systematic review of existing literature

Tzelves,

Nagasubramanian,

Pinitas

et al. 2023

Therapeutic Advances in Urology

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Introduction: Transperineal laser ablation (TPLA) of the prostate is a new, minimally invasive technique for benign prostatic hyperplasia (BPH) with promising effectiveness and safety outcomes. This systematic review aims to provide an update of existing literature. Methods: A literature review was performed in Pubmed/MEDLINE, Embase, Cochrane Library, and clinicaltrials.gov from January 2000 up to April 2023. Data extraction and risk of bias were performed independently by three authors. Results: A total of 11 studies were included, among which 9 were observational, 1 randomized controlled trial, 1 animal study, while 2 of them were comparative (1 with prostatic artery embolization and 1 with transurethral resection of the prostate). Functional outcomes were improved in the majority of studies both for objective (maximum flow rate and post-void residual) and subjective outcomes (improvement of International Prostate Symptom Score and quality of life). Complication rates ranged between 1.9% and 2.3% for hematuria, 3.7% and 36.3% for dysuria, 1.9% and 19% for acute urinary retention, 0.6% and 9.1% for orchitis/urinary tract infections, and 0.6% and 4.8% for prostatic abscess formation. Regarding sexual function, >95% of patients retained their ejaculation while erectile function was maintained or improved. Conclusion: TPLA of the prostate is an innovative, minimally invasive technique for managing patients with BPH. Existing studies indicate an effective technique in reducing International Prostate Symptom Score and quality of life scores, post-void residual reduction, and increase in Qmax, albeit the measured improvements in terms of Qmax are not equal to transurethral resection of the prostate. Although sexual function is maintained, the mean catheterization time is 7 days, and no long-term data are available for most patients.

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Section: Resultsmentioning

confidence: 99%