Ultrasound-guided transrectal extended prostate biopsy: a prospective study

Abstract

The 10 systematic TRUS-guided prostate biopsy improves the detection rate of prostate cancer by 28.6% when compared with the sextant biopsy technique alone, without increase in the morbidity. We therefore recommend the 10-core biopsy protocol to be the preferred method for early detection of prostate cancer.

Operator is an Independent Predictor of Detecting Prostate Cancer at Transrectal Ultrasound Guided Prostate Biopsy

“…The overall cancer detection rate in this study was previously reported at almost 50%, 14,15 which is higher than in traditional series with a rate of 27% to 44% in similar cohorts. [22][23][24][25][26][27][28] This is similar to findings in studies of saturation techniques for initial biopsy with a 43% to 46% rate. 19,29 We believe that our high detection rate is explained by solid techniques, significant case load, excellent equipment, end firing probes and ultrasound to find hypoechoic lesions which, as we already reported, increases the yield.…”

Individualized prostate biopsy strategy for Chinese patients with different prostate-specific antigen levels

“…The overall cancer detection rate was 40.7% in our patients. This rate is higher than the data from some contemporary developed-world studies [5,[7][8][9][10]. The median patient age, median PSA level, median PSAD, abnormal DRE rate and abnormal TRUS rate were significantly higher in our cancer patients than in non-cancer patients, consistent with previous developed-world studies [7,8,10].…”

“…Although the TRUS-guided prostate biopsy is the gold standard for diagnosing prostate cancer, the best strategy for biopsy remains controversial [9]. An increasing number of studies from developed countries indicate that the traditional sextant biopsy strategy is insufficient for diagnosing prostate cancer as compared with the extended biopsy strategies, which detect probably 30% more cancers without increasing the number of clinically insignificant cancers [5,[8][9][10]. TRUS-guided prostate biopsy has not been wildly applied in China and other developing countries.…”

Transrectal ultrasound guided biopsy for detecting prostate cancer: can random biopsies be reduced using the 4-dimensional technique?

“…Isoechoic cancer rate reported by Ghazo et al was 37.3% [21] and in our study the rate was 26.7%. The additional yield of clinically significant carcinoma found at random biopsy sites, where no lesion was detected by TRUS, warrants the continued use of systematic TRUS guided biopsy in the evaluation of patients with abnormal DRE or PSA findings.…”

“…Increasing the number of biopsies seems to be the proposed solution to elevate sensitivity although with some loss in specificity and less patient tolerance [6]. A total of 10 cores were reported to improve detection by 28.6% [21]. Fink also reported that the 10-core biopsy was superior [25].…”