Ultrasound in schistosomiasis mansoni

Pinto-Silva, Rogério Augusto; Queiroz, Leonardo Campos de; Azeredo, Letícia Martins; Silva, Luciana Cristina dos Santos; Lambertucci, José Roberto

doi:10.1590/s0074-02762010000400021

Cited by 39 publications

(27 citation statements)

References 32 publications

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“…Since US is a convenient and reliable method, it is routinely used in the diagnosis and evaluation of patients with schistosomiasis (288)(289)(290). US can be used to demonstrate classical features of schistosomal hepatic damage, such as periportal fibrosis, appearing as "bulls-eye" lesions, a network echogenic pattern, hepatic granulomas, and gallbladder thickening (291,292).…”

Section: Diagnosis and Evaluation Of Schistosome-induced Liver Diseasementioning

confidence: 99%

Advances in the Diagnosis of Human Schistosomiasis

et al. 2015

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SUMMARY Schistosomiasis is a major neglected tropical disease that afflicts more than 240 million people, including many children and young adults, in the tropics and subtropics. The disease is characterized by chronic infections with significant residual morbidity and is of considerable public health importance, with substantial socioeconomic impacts on impoverished communities. Morbidity reduction and eventual elimination through integrated intervention measures are the focuses of current schistosomiasis control programs. Precise diagnosis of schistosome infections, in both mammalian and snail intermediate hosts, will play a pivotal role in achieving these goals. Nevertheless, despite extensive efforts over several decades, the search for sensitive and specific diagnostics for schistosomiasis is ongoing. Here we review the area, paying attention to earlier approaches but emphasizing recent developments in the search for new diagnostics for schistosomiasis with practical applications in the research laboratory, the clinic, and the field. Careful and rigorous validation of these assays and their cost-effectiveness will be needed, however, prior to their adoption in support of policy decisions for national public health programs aimed at the control and elimination of schistosomiasis.

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Section: Diagnosis and Evaluation Of Schistosome-induced Liver Diseasementioning

confidence: 99%

Advances in the Diagnosis of Human Schistosomiasis

et al. 2015

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“…The most important fi ndings are echogenic thickening of the walls of the portal vein and its branches, indicative of periportal fi brosis, and echogenic enlargement of the gallbladder wall. However, US is a subjective procedure and is therefore examiner-dependent [23][24][25][26][27][28][29][30][31][32] .…”

Section: Ultrasound In Hepatosplenic Schistosomiasismentioning

confidence: 99%

Revisiting the concept of hepatosplenic schistosomiasis and its challenges using traditional and new tools

Lambertucci

2014

Rev. Soc. Bras. Med. Trop.

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Different aspects of hepatosplenic schistosomiasis are revisited here. Manson's schistosomiasis causes periportal fi brosis and portal hypertension in approximately 6% of infected subjects, usually with preservation of their hepatic function. The assessment of liver involvement is of major importance in determining the prognosis and risk of complications from schistosomiasis, such as upper digestive bleeding secondary to variceal rupture. For many years, the diagnosis of hepatosplenic schistosomiasis and liver fi brosis was made by abdominal palpation and the fi nding of liver and/or spleen enlargement. However, there is no consensus regarding the clinical parameters of the liver and spleen to be considered in this physical evaluation. For the last three decades, abdominal ultrasound (US) has become the best imaging technique to evaluate liver fi brosis caused by schistosomiasis mansoni. However, US is a subjective procedure and is therefore examiner-dependent. Magnetic resonance imaging (MRI) fi ndings have provided valuable information in addition to ultrasound and clinical examination. The combination of a comprehensive history and physical examination, basic laboratory tests (a stool examination for Schistosoma mansoni eggs and a blood cell count), biomarkers for liver fi brosis/portal hypertension and imaging methods seem to offer the best approach for evaluating patients with this disease. In situations where research is involved or in patients with severe disease, MRI may be considered.

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“…The patient's risk for variceal bleeding increases when portal hypertension is present. Sonographic changes suggestive of portal hypertension are an increased diameter of the portal vein (normally < 12 mm in adults) or splenic vein (normally < 9 mm), 68 the presence of ascites, and the development of portosystemic collateral vessels. 59 The most commonly described collateral veins are the perigastric, the paraumbilical, and the splenorenal veins.…”

Section: Other Infectious Diseases With Potential For Pocus Applicationmentioning

confidence: 99%

“…Detection is increased by color Doppler, which also allows detection of hepatofugal circulation. 68 Enlargement of the caudate lobe compared with the right lobe is another finding, which is relatively easy to visualize by US, and reflects changes in portal blood supply in the cirrhotic liver. Caudate lobe enlargement has been described in patients with schistosomiasis.…”

Section: Other Infectious Diseases With Potential For Pocus Applicationmentioning

confidence: 99%

Point-of-Care Ultrasound Assessment of Tropical Infectious Diseases—A Review of Applications and Perspectives

Bélard¹,

Tamarozzi²,

Bustinduy³

et al. 2016

The American Society of Tropical Medicine and Hygiene

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Abstract. The development of good quality and affordable ultrasound machines has led to the establishment and implementation of numerous point-of-care ultrasound (POCUS) protocols in various medical disciplines. POCUS for major infectious diseases endemic in tropical regions has received less attention, despite its likely even more pronounced benefit for populations with limited access to imaging infrastructure. Focused assessment with sonography for HIV-associated TB (FASH) and echinococcosis (FASE) are the only two POCUS protocols for tropical infectious diseases, which have been formally investigated and which have been implemented in routine patient care today. This review collates the available evidence for FASH and FASE, and discusses sonographic experiences reported for urinary and intestinal schistosomiasis, lymphatic filariasis, viral hemorrhagic fevers, amebic liver abscess, and visceral leishmaniasis. Potential POCUS protocols are suggested and technical as well as training aspects in the context of resourcelimited settings are reviewed. Using the focused approach for tropical infectious diseases will make ultrasound diagnosis available to patients who would otherwise have very limited or no access to medical imaging.

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Ultrasound in schistosomiasis mansoni

Cited by 39 publications

References 32 publications

Advances in the Diagnosis of Human Schistosomiasis

Advances in the Diagnosis of Human Schistosomiasis

Revisiting the concept of hepatosplenic schistosomiasis and its challenges using traditional and new tools

Point-of-Care Ultrasound Assessment of Tropical Infectious Diseases—A Review of Applications and Perspectives

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