Ultrasound-mediated multifunctional magnetic microbubbles for drug delivery of celastrol in VX2 liver transplant tumors

Drug delivery particles for targeted imaging-guided photothermal/chemotherapy synergy cancer therapy

“…Among many nanocarriers, the polymer poly (lactide- co -glycolic acid) (PLGA) has good biodegradability and biocompatibility, and its surface can be easily modified with other ligands or functional groups and has been widely studied [ 13 , 14 ]. SPIO is an inorganic photothermal material and MRI T 2 -weighted contrast agent that has been certified by the U.S. Food and Drug Administration (FDA) and can be used in clinical research [ 15 , 16 ]. PFH is a fluorocarbon substance with good stability.…”

A pH-Responsive Nanoplatform Based on Magnetic Mesoporous Silica Nanoparticles for Enhanced Treatment of Pancreatic Cancer

“…The rapid evolution of nanotechnology has facilitated the evolution of various types of functional nano systems that may enable the precise diagnosis and treating of pancreatic carcinoma. − In particular, multifunctional nanosystems that integrate drug delivery and imaging functions can achieve precise positioning and controlled drug release at the tumor site, thereby maximizing the therapeutic potential of anticancer drugs while reducing damage to normal tissues. This is considered to be an effective method of achieving precision treatment of pancreatic cancer. Currently, various functional nano systems that have been designed to treat pancreatic cancer have shown good results. − However, many of these nano systems can release drugs prematurely and have problems such as fast elimination in vivo, which can limit the therapeutic effect . Therefore, the design of a nano system that integrates multiple diagnostic functions and respond to the tumor microenvironment to achieve precisely controlled drug release has become a priority for pancreatic cancer precision therapy.…”