Ultrasound versus 'clinical touch' for catheter guidance during embryo transfer in women

Brown, Julie; Buckingham, Karen; Buckett, William; Abou‐Setta, Ahmed M

doi:10.1002/14651858.cd006107.pub4

Cited by 49 publications

(16 citation statements)

References 61 publications

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“…In the last few years of the study period, the CS-group had an echogenic catheter and ultrasound for the embryo transfer, as shown in Table 1. Currently there is little evidence that ultrasound-guided embryo transfer improves pregnancy outcomes (Brown, Buckingham, Abou-Setta, & Buckett, 2010;Brown, Buckingham, Buckett, & Abou-Setta, 2016). Separate analysis of live birth rate did not show a significant difference between the two periods (data not shown).…”

Section: Discussionmentioning

confidence: 89%

Previous caesarean section is associated with lower subsequent in vitro fertilization live birth rates

et al. 2019

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This retrospective cohort study examines the association between previous mode of delivery and subsequent live birth rate in women who become pregnant after in vitro fertilization (IVF) or intra cytoplasmic sperm injection (ICSI) after their first delivery. The study included 112 women with a previous caesarean section and 418 women with a previous vaginal delivery, and a total of 1588 embryo transfers between January 2005 and June 2016 (Leiden University Medical Centre, the Netherlands). The mean age was 35 years and mean number of embryos transferred per attempt, 1.18. The study population included a total of 429 pregnancies resulting in 296 live births. The crude odds ratio for a subsequent live birth per embryo transfer was 0.60 (CI; 0.44 to 0.83, p ¼ 0.002) in women with a previous caesarean section compared to women with a previous vaginal delivery. After adjustment for age, fresh/frozen-thawed embryo transfer and quality of the embryo, the odds ratio was 0.64 (CI; 0.46 to 0.89, p ¼ 0.01). It was concluded that in subfertile women trying to achieve a subsequent pregnancy with IVF or ICSI, a history of caesarean section was associated with a reduced live birth rate per embryo transfer compared to women with a history of one previous vaginal delivery.

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Section: Discussionmentioning

confidence: 89%

Previous caesarean section is associated with lower subsequent in vitro fertilization live birth rates

et al. 2019

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“…In our study, the clinical pregnancy rate was the same in both groups, and using transabdominal ultrasound for insemination provided no added benefits to the clinicians or patients. For embryo transfer in IVF, ultrasound guidance leads to an increase in the pregnancy and live birth rates [11]. In IVF, the cervical and uterine manipulations during catheterization can induce contractions and endometrial trauma that may lead to expulsion of the embryo [15-17].…”

Section: Discussionmentioning

confidence: 99%

“…The majority of published studies on IUI have focused on ovarian stimulation and seminal fluid parameters, instead of on the technique of insemination itself [10]. For IVF procedures, in 2016, the Cochrane Database of Systematic Reviews presented an analysis of 21 RCTs comparing ultrasound guidance during embryo transfer versus the blind method, which relies on the clinician’s tactile senses to judge if the catheter is in the correct position, and concluded that ultrasound guidance led to higher clinical pregnancy rates and live birth rates than the blind method of embryo transfer [11]. Therefore, we sought to determine whether the same technique using transabdominal ultrasound guidance during intrauterine catheter insemination (US-IUI), compared to the blind method IUI without ultrasound guidance (BM-IUI), improved clinical pregnancy rates in IUI treatment cycles.…”

Section: Introductionmentioning

confidence: 99%

Ultrasound guidance versus the blind method for intrauterine catheter insemination: A randomized controlled trial

Mubarak

Yusoff

Adnan

2019

Clin Exp Reprod Med

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Objective The primary objective of this study was to compare clinical pregnancy rates in intrauterine insemination (IUI) treatment cycles with transabdominal ultrasound guidance during intrauterine catheter insemination (US-IUI) versus the “blind method” IUI without ultrasound guidance (BM-IUI). The secondary objective was to compare whether US-IUI had better patient tolerability and whether US-IUI made the insemination procedure easier for the clinician to perform compared to BM-IUI. Methods This was a randomized controlled trial done at the Reproductive Medicine Unit of General Hospital Kuala Lumpur, Malaysia. We included women aged between 25 and 40 years who underwent an IUI treatment cycle with follicle-stimulating hormone injections for controlled ovarian stimulation. Results A total of 130 patients were recruited for our study. The US-IUI group had 70 patients and the BM-IUI group had 60 patients. The clinical pregnancy rate was 10% in both groups ( p > 0.995) and there were no significant difference between the groups for patient tolerability assessed by scores on a pain visual analog scale ( p = 0.175) or level of difficulty for the clinician ( p > 0.995). The multivariate analysis further showed no significant increase in the clinical pregnancy rate (adjusted odds ratio, 1.07; 95% confidence interval, 0.85–1.34; p = 0.558) in the US-IUI group compared to the BM-IUI group even after adjusting for potential covariates. Conclusion The conventional blind method for intrauterine catheter insemination is recommended for patients undergoing IUI treatment. The use of ultrasound during the insemination procedure increased the need for trained personnel to perform ultrasonography and increased the cost, but added no extra benefits for patients or clinicians.

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“…Among the most important variables that determine the success or failure of the procedure are: ultrasound guidance ( Brown et al , 2016 ), uterine contractions during ET ( Pierzyński & Zbucka-Kretowska, 2014 ), and the catheter type used during the procedure ( Buckett, 2006 ). A few years ago, the type of catheter chosen was recognized as one of the main variables interfering positively or negatively on the ET effectiveness.…”

Section: Introductionmentioning

confidence: 99%

A prospective study comparing two embryo-transfer soft catheters

Conto

Schuster

Genro

et al. 2017

JBRA Assisted Reproduction

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ObjectivesTo compare reproductive outcomes using two different soft catheters i.e. Set TDT® and Cook® Sydney IVF. The primary outcome was defined as a positive β-human chorionic gonadotropin (β-hCG) test.MethodsOur prospective study recruited 68 patients undergoing in vitro fertilization cycles in a private fertility clinic in Porto Alegre, Brazil, between January 2014 and April 2016. They were divided into two groups according to the catheter that would be used for the embryo transfer, and the groups were matched by age. The total number of patients in each group was: 34 for the TDT and 34 for the Cook Sydney. All the patients were submitted to a β-hCG test 12 days after the embryo transfer for pregnancy outcome evaluation.ResultsTen out of 34 patients from the TDT group had a positive outcome for pregnancy, corresponding to 29.4%. The Cook Sydney group had 9 patients out of 34 with positive outcomes, corresponding to 26.5%. Comparing the efficacy of both catheters for the primary outcome, there was no significant difference (p>0.05) between the TDT and the Cook Sydney catheters.ConclusionThe TDT and the Cook Sydney catheters efficacies were similar for embryo transfer during assisted reproductive technology cycles.

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Ultrasound versus 'clinical touch' for catheter guidance during embryo transfer in women

Cited by 49 publications

References 61 publications

Previous caesarean section is associated with lower subsequent in vitro fertilization live birth rates

Previous caesarean section is associated with lower subsequent in vitro fertilization live birth rates

Ultrasound guidance versus the blind method for intrauterine catheter insemination: A randomized controlled trial

A prospective study comparing two embryo-transfer soft catheters

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