Ultrastructural Analysis of the Prostate Gland under the Effect of Factors of Chemical Industry

Abstract

We analyzed ultrastruciture of the cell populations in the prostate gland in chronic nonbacterial prostatitis in a chemical industry worker. It was shown that ultrastructural reorganization of the epithelium consisted in reduction of the secretory compartment of the cytoplasm and dystrophic-degenerative changes in cell organelles. Endothelial cells of the capillaries showed signs of significant degeneration and low intensity of micropinocytosis. Most of the smooth muscle cells underwent dystrophic-degenerative modifications of ultrastructural elements. The dominance of degenerative cell changes in the epithelial and stromal cell populations along with intensification of collagen formation in the absence of inflammatory elements allows us to interpret this pathological condition of the prostate gland as prostate pathology of occupational or mixed genesis.

Histomorphmetric studies on the protective role of Maca (Lepidium meyenii) on New Zealand White Rabbits prostate gland under oxidative stress

“…However, in H2O2 groups, the acini's epithelium shown degenerative alterations and the secretion reduced markedly. So, this implies that the gland isn't functioning, which results in a lower secretory capability (Nepomnyashchikh, 2014). Rats given BPA at a dose of 100 g/kg showed identical deterioration of the muscle and blood vessel congestion as those in the H2O2 groups, and this alteration may lead to tissue damage (Hasanluyi et al, 2016).…”