Ultrastructural Recognition of Cells with Dendritic Cell Morphology in Human Aortic Intima. Contacting Interactions of Vascular Dendritic Cells in Athero-resistant and Athero-prone Areas of the Normal Aorta.

Detection of Vascular Dendritic Cells and Extracellular Calcium-Binding Protein S-100 in Foci of Calcification in Human Arteries.

“…Vascular dendritic cells manifest ultrastructural features typical of antigen-presenting dendritic cells and they cluster with lymphocytes [7]. Vascular dendritic cells were detected in atherosclerotic plaques more frequently than in nonatherosclerotic arterial intima [6,7].…”

“…Recently we described the presence of CDIa+/S-100+ vascular dendritic cells in the arterial wall [6,7] . Vascular dendritic cells manifest ultrastructural features typical of antigen-presenting dendritic cells and they cluster with lymphocytes [7].…”

“…[7]. This process should result in the release of their cellular components into the extracellular space including S-100 which belongs to the family of calcium-binding pro-teins [19].…”

Dendritic Cells in Atherogenesis: Possible Novel Targets for Prevention of Atherosclerosis

“…Although all the subtypes described above contribute to vascular DCs, most vascular DCs are probably cDCs and inflammatory DCs. Boryshev et al identified vascular DCs in normal arteries and proposed that vascular DCs might play an important role in the development of atherosclerotic lesions 27,28) . Immature DCs (CD1a ＋ S-100…”

Role of dendritic cells in cardiovascular diseases

“…DCs have been reported to occur in the adventitia and intima of large arteries, including aorta, coronary and carotid arteries [40] . In contrast, DCs were not present in normal veins and they only occurred in diseased veins after vessel injury [41] .…”