Ultrastructure of the nephron of the one‐humped camel, <i>Camelus dromedarius</i>

Safer, A. M.; El-Sayed, N. K.; Abo-Salem, K. S.; Al-Shaer, R.

doi:10.1002/jmor.1051980304

Cited by 9 publications

(6 citation statements)

References 13 publications

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“…Urea could be recycled from the pelvic urine in species in which the renal pelvis forms folds which facilitate recycling of urea to build up osmotic concentration in the medulla [12,13,14]. Although the morphology of the kidneys of camels has been the subject of some studies [15,16,17], no precise description of the structure of the renal pelvis and its anatomical and functional relationship to the medulla in the dromedary camel is found in the literature. The study of the normal architecture of the mammalian renal pelvis may have clinical significance.…”

Section: Introductionmentioning

confidence: 99%

Anatomical features in the kidney involved in water conservation through urine concentration in dromedaries (Camelus dromedarius)

Abdalla

2020

Heliyon

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A B S T R A C TThe aim of this study was to report some of the morphological characteristics of the kidney involved in urine concentration and hence water conservation in the dromedaries. A total of 20 fresh kidneys of 10 apparently healthy camels were used in this study. The architecture of the renal pelvis was revealed by dissection and polyvinyl chloride corrosion casts. Samples were also processed for histology and for enzyme histochemistry. The camel kidney is bean shaped, smooth, multilobar, unipapillary, in which the fusion of renal papillae is complete forming a common renal papilla or crest, which channel urine into a central renal pelvis. It is more or less similar to equine, caprine, ovine and canine kidney. Under certain anatomical requisites the renal pelvis is known to play a role in urine concentration through recycling of urea to increase the medullary osmotic concentration which favors the counter-current mechanism. One of these requisites is an elaborate renal pelvis which is closely associated with the renal medulla. The renal pelvis of the camel has a main crescentic cavity following the long axis and curvature of the kidney. A thick extensive renal crest projects into the cavity of the pelvis. The thick renal crest contains large numbers of long loops of Henle and vasa recta which are important for urine concentration. The renal crest is formed by convergence of the medullary pyramids before it projects into the cavity of the renal pelvis. The crescentic main cavity of the pelvis forms 20-24 three dimensional radiating collateral recesses which contain the medullary pyramids. This close association of the renal pelvis and medulla provide a large surface area for the recycling of urea and hence urine concentration. This large pelvic-medullary interface is lined by simple low cuboidal epithelium which enhances the recycling of urea and water from the pelvic urine into the medulla and directly contributes to urine concentration. The rest of the wall of the renal pelvis and its recesses facing away from the renal crest and medullary pyramids is lined by impermeable transitional epithelium. Another feature is the intense activity of alkaline phosphatase demonstrated in the proximal convoluted tubules which indicates increased membrane transport. It is concluded that the kidney in dromedaries has the anatomical and histochemical requisites for the production of concentrated urine. These requisites enable the kidney to adequately contribute to the ability of the camel to conserve water and withstand the aridity of its habitat.

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Section: Introductionmentioning

confidence: 99%

Anatomical features in the kidney involved in water conservation through urine concentration in dromedaries (Camelus dromedarius)

Abdalla

2020

Heliyon

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“…In the latter, the membrane usually appears lamellated and contains numerous tiny vesicles. In other parts of the nephron, the basal lamina usually has a homogenous appearance (Safer et al, 1988).…”

Section: Discussionmentioning

confidence: 99%

Light and Electron Microscopic Features of the Kidney in Hedgehog (Hemiechinus auritus)

Nabipour

Dehghani

2012

Journal of Veterinary Anatomy

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“…Both are likely featured as round to oval and sometimes show irregular loaded structures (50-500 nm) with a unit membrane surrounded by a pale halo [Safer et al, 1988[Safer et al, , 1990Abou-Salem. 1988;Al-Ajmi, 1988;Safer and Katchburian, 1991).…”

Section: Discussionmentioning

confidence: 99%

“…Such vesicles are believed to originate as projections of osteoblasts and the cell mem brane of chondrocytes Severs, 1982, 1983;Anderson. 1985;El-Mardi, 1987], However, results from recent studies report that the membrane-bound bod ies may be pinched off from the crista constrictions of the basal infoldings of the cells by sending finger-like projec tions to the thick subjacent basal laminae of the epithelial cells [Safer et al. 1988[Safer et al.…”

Section: Introductionmentioning

confidence: 99%

“…Recently, ultrastructural approaches to the kidney cells of both the camel Camelus dromedarius and the gerbil Meriones crassus have shown the existence of well-elabo rated thick basal laminae in most parts of the ncphronic tubules, accompanied by a unique, random population of vesicular bodies (50-500 nm) in the camel [Safer et al, 1988; Abou-Salcm, 1988] as well as in the gerbil [Safer et al., 1990). The vesicular bodies are more or less round to oval in shape, their interior with elemental contents [Safer and Botros, 1989], Freeze-fracture studies indicated that these vesicles were surrounded by a typical unit memReceived: October 21.…”

Section: Introductionmentioning

confidence: 99%

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Possible Biogenesis of the Membrane-Bound Bodies of the Thick Basal Laminae of the Proximal Convoluted Tubule Cells of the Gerbil Meriones crassus

Safer

1992

Cells Tissues Organs

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The ultrastructural findings on the kidney cells of the gerbil Meriones crαssus have shown the presence of finger-like projections emerging from the basal part of the epithelial cells of the proximal convoluted tubules into the matrix of the thick basal laminae and that structure like membrane-bound bodies are commonly seen in continuity with these processes. Such findings would give clues for the possible biogenesis of the membrane-bound bodies from the epithelial cells. Such an origin is consistent with the idea that either all or part of the population of membrane-bound bodies is produced by a process of budding off from the basal cell membrane rather than by extension of an intracytoplasmic precursor through the plasma membrane.

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Ultrastructure of the nephron of the one‐humped camel, Camelus dromedarius

Cited by 9 publications

References 13 publications

Anatomical features in the kidney involved in water conservation through urine concentration in dromedaries (Camelus dromedarius)

Anatomical features in the kidney involved in water conservation through urine concentration in dromedaries (Camelus dromedarius)

Light and Electron Microscopic Features of the Kidney in Hedgehog (Hemiechinus auritus)

Possible Biogenesis of the Membrane-Bound Bodies of the Thick Basal Laminae of the Proximal Convoluted Tubule Cells of the Gerbil Meriones crassus

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