Ultrathin porous Pd metallene as highly efficient oxidase mimics for colorimetric analysis

Zhao, Xiaoxue; Li, Zhe; Ding, Zhenyu; Wang, Shuna; Lu, Yizhong

doi:10.1016/j.jcis.2022.06.124

Cited by 30 publications

(12 citation statements)

References 49 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…As a mimic of natural enzymes, nanozyme has been widely used in biosensing because of its low cost, good stability, and durability. − As shown in Figure a, due to the excellent oxidase-like activity of Co–N x (C), it can oxidize colorless TMB to blue oxidized TMB (oxTMB), while oxTMB can be reduced when some reductive small molecules such as ascorbic acid (AA), glutathione (GSH), cysteine (Cys), or dopamine (DA) are introduced into the reaction system. In addition, in our previous work, − we also reported that the reaction of biological enzymes such as alkaline phosphatase (ALP), acid phosphatase (ACP), and α-glucosidase (α-Glu) with the corresponding substrates of 2-phospho- l -ascorbic acid (AAP) and l -ascorbic acid-2- O -α- d -glucopyranosyl (AAG) respectively can produce AA. We tried to compare the oxidase-like activity of Co–N x (C) by comparing their ability to consume these reducing substances as well as the biological enzymes under the same conditions.…”

Section: Resultsmentioning

confidence: 99%

Regulating the N Coordination Environment of Co Single-Atom Nanozymes for Highly Efficient Oxidase Mimics

et al. 2023

Self Cite

View full text Add to dashboard Cite

Single-atom catalysts with well-defined atomic structures and precisely regulated coordination environments have been recognized as potential substitutes for natural metalloenzymes. Inspired by the metal coordination structure of natural enzymes, we show here that the oxidase-like activity of single-atom Co catalysts greatly depends on their local N coordination around the Co catalytic sites. We synthesized a series of Co single-atom catalysts with different nitrogen coordination numbers (Co–N x (C), x = 2, 3, and 4) and demonstrated that the oxidase-like activity of single-atom Co catalysts could be effectively tailored by fine-tuning the N coordination. Among the studied single-atom Co catalysts, the Co–N3(C) with three-coordinate N atoms shows the optimum oxygen adsorption structure and robust reactive oxygen species (ROS) generation, thus presenting the preferable oxidase-like catalytic activity. This work facilitates the future development of rational nanozyme designs for targeting reactions at the atomic level.

show abstract

Section: Resultsmentioning

confidence: 99%

Regulating the N Coordination Environment of Co Single-Atom Nanozymes for Highly Efficient Oxidase Mimics

et al. 2023

Self Cite

View full text Add to dashboard Cite

show abstract

“…Then, the reaction time, catalyst dosage, pH, and temperature were considered to be main factors affecting the oxidase-like activity of OVs-Mn 2 O 3 -400 . As shown in Figure D, the reaction system of OVs-Mn 2 O 3 -400/TMB showed the enhanced absorbance value at 652 nm with the increase of catalyst dosage.…”

Section: Resultsmentioning

confidence: 99%

Nanozyme Rich in Oxygen Vacancies Derived from Mn-Based Metal–Organic Gel for the Determination of Alkaline Phosphatase

Song

Huang

2023

Inorg. Chem.

View full text Add to dashboard Cite

Vacancy engineering as an effective strategy has been widely employed to regulate the enzyme−mimic activity of nanomaterials by adjusting the surface, electronic structure, and creating more active sites. Herein, we purposed a facile and simple method to acquire transition metal manganese oxide rich in oxygen vacancies (OVs-Mn 2 O 3 -400) by pyrolyzing the precursor of the Mn(II)-based metal−organic gel directly. The as-prepared OVs-Mn 2 O 3 -400 exhibited superior oxidase-like activity as oxygen vacancies participated in the generation of O 2•− . Besides, steady state kinetic constant (K m ) and catalytic kinetic constant (E a ) suggested that OVs-Mn 2 O 3 -400 had a stronger affinity toward 3,3′,5,5′-tetramethylbenzidine and possessed prominent catalytic performance. By taking 2-phospho-Lascorbic acid as the substrate, which can be converted into reducing substance ascorbic acid in the presence of alkaline phosphatase (ALP), OVs-Mn 2 O 3 -400 can be applied as an efficient nanozyme for ALP colorimetric analysis without the help of destructive H 2 O 2 . The colorimetric sensor established by OVs-Mn 2 O 3 -400 for ALP detection showed a good linearity from 0.1 to 12 U/L and a lower limit of detection of 0.054 U/L. Our work paves the way for designing enhanced enzyme-like activity nanozymes, which is of significance in biosensing.

show abstract

“…Lu et al synthesized an ultrathin porous palladium (Pd) nanozyme exhibiting peroxidase (POD)-like activity. It was used for TAC evaluation in food owing to its positive catalytic performance . Further, Wang et al reported a colorimetric method based on iron–manganese (Fe–Mn) bimetallic nanozymes to determine the TAC in kiwi fruit .…”

Section: Introductionmentioning

confidence: 99%

“…It was used for TAC evaluation in food owing to its positive catalytic performance. 15 Further, Wang et al reported a colorimetric method based on iron− manganese (Fe−Mn) bimetallic nanozymes to determine the TAC in kiwi fruit. 16 Although nanozymes have many advantages, such as easy synthesis and high stability, the POD-like activities of these nanozymes are far lower than those of natural enzymes.…”

Section: Introductionmentioning

confidence: 99%

Palladium/Rhodium/Iridium Trimetallic Octahedral Nanozymes Exhibiting Enhanced Peroxidase-like Activity for Detecting Total Antioxidant Capacity in Food

Yang

et al. 2023

ACS Appl. Nano Mater.

View full text Add to dashboard Cite

Nanozymes are widely used in detecting biomarkers. However, designing nanozymes exhibiting high peroxidase-like activity is challenging. This study aimed to synthesize two types of nanozymes, Pd−Rh−Ir nanozyme (PRI nanozyme) and Pd−Ir nanozyme (PI nanozyme), exhibiting similar morphologies and enhanced activities. The first nanozyme comprised palladium, rhodium, and iridium (PRI nanozyme), while the second nanozyme comprised palladium and iridium (PI nanozyme). The PRI nanozyme exhibited a higher peroxidase-like activity than the PI nanozyme. Rhodium in the subsurface of the PRI nanozyme can lower the hydrogen peroxide decomposition energy and increase the hydroxyl radical (•OH) content in a catalytic system. As a proof of concept, the PRI nanozyme was used to detect ascorbic acid, cysteine, and glutathione, with limits of detection (LODs) being 0.14, 0.18, and 0.21 μM, respectively. Finally, the PRI nanozymebased method was applied to determine the total antioxidant capacities (TACs) of different beverages, fruits, and vegetables. Among the tested samples, Actinidia Chinensis Planch exhibited the highest TAC. This study broadens the application of multimetallic nanozymes in the field of food quality and safety.

show abstract

Ultrathin porous Pd metallene as highly efficient oxidase mimics for colorimetric analysis

Cited by 30 publications

References 49 publications

Regulating the N Coordination Environment of Co Single-Atom Nanozymes for Highly Efficient Oxidase Mimics

Regulating the N Coordination Environment of Co Single-Atom Nanozymes for Highly Efficient Oxidase Mimics

Nanozyme Rich in Oxygen Vacancies Derived from Mn-Based Metal–Organic Gel for the Determination of Alkaline Phosphatase

Palladium/Rhodium/Iridium Trimetallic Octahedral Nanozymes Exhibiting Enhanced Peroxidase-like Activity for Detecting Total Antioxidant Capacity in Food

Contact Info

Product

Resources

About