Ultraviolet-C decontamination of a hospital room: Amount of UV light needed

Lindblad, Marie; Tano, Eva; Lindahl, Claes; Huss, Fredrik

doi:10.1016/j.burns.2019.10.004

Cited by 93 publications

(97 citation statements)

References 20 publications

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“…Across the ultraviolet (UV) light spectrum that is invisible to the human eye, for the purposes of this review, there are three classifications according to wavelength: UVA (320–400 nm), UVB (280–320 nm), and UVC (200–280 nm) [ 45 ]. UVC light has much stronger germicidal properties than both UVA and UVB [ 46 , 47 ]. UVC is strongly absorbed by RNA and DNA bases, leading to molecular structural damage via a photodimerization process; this results in virus inactivation, as the virus is no longer able to replicate [ 47 , 48 ].…”

Section: Disinfectionmentioning

confidence: 99%

“…UVC light has much stronger germicidal properties than both UVA and UVB [ 46 , 47 ]. UVC is strongly absorbed by RNA and DNA bases, leading to molecular structural damage via a photodimerization process; this results in virus inactivation, as the virus is no longer able to replicate [ 47 , 48 ]. Thus, for PPE decontamination, the focus is on UVC rather than UVA or UVB.…”

Section: Disinfectionmentioning

confidence: 99%

“…While there is no doubt that UVC is effective against both SARS-CoV-1 and SARS-CoV-2, efficacy of the applied dose (a function of irradiance and time) appears to be highly dependent on many factors, such as virus titre, inoculum size, the virus medium, and both shape, contours and type of material [ 30 , 47 , 51 , 58 ], likely explaining the highly inconsistent findings in the published literature. However, based on the available evidence, it seems that the effect of relative humidity on UVGI efficacy can be considered negligible [ 59 ].…”

Section: Disinfectionmentioning

confidence: 99%

See 2 more Smart Citations

Rapid Review of SARS-CoV-1 and SARS-CoV-2 Viability, Susceptibility to Treatment, and the Disinfection and Reuse of PPE, Particularly Filtering Facepiece Respirators

Derraik

Anderson

Connelly

et al. 2020

IJERPH

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In the COVID-19 pandemic caused by SARS-CoV-2, hospitals are often stretched beyond capacity. There are widespread reports of dwindling supplies of personal protective equipment (PPE), particularly N95-type filtering facepiece respirators (FFRs), which are paramount to protect frontline medical/nursing staff, and to minimize further spread of the virus. We carried out a rapid review to summarize the existing literature on the viability of SARS-CoV-2, the efficacy of key potential disinfection procedures against the virus (specifically ultraviolet light and heat), and the impact of these procedures on FFR performance, material integrity, and/or fit. In light of the recent discovery of SARS-CoV-2 and limited associated research, our review also focused on the closely related SARS-CoV-1. We propose a possible whole-of-PPE disinfection solution for potential reuse that could be rapidly instituted in many health care settings, without significant investments in equipment.

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Section: Disinfectionmentioning

confidence: 99%

Section: Disinfectionmentioning

confidence: 99%

Section: Disinfectionmentioning

confidence: 99%

See 1 more Smart Citation

Rapid Review of SARS-CoV-1 and SARS-CoV-2 Viability, Susceptibility to Treatment, and the Disinfection and Reuse of PPE, Particularly Filtering Facepiece Respirators

Derraik

Anderson

Connelly

et al. 2020

IJERPH

View full text Add to dashboard Cite

show abstract

“…Across the ultraviolet (UV) light spectrum, there are three classifications: UVA (320-400 nm), UVB (280-320 nm), and UVC (200-280 nm) 18 . UVC light has much stronger germicidal properties than both UVA and UVB 19,20 . UVC is strongly absorbed by RNA and DNA bases leading to molecular structural damage via a photodimerization process.…”

Section: Ultraviolet Germicidal Irradiation (Uvgi)mentioning

confidence: 99%

Rapid evidence summary on SARS-CoV-2 survivorship and disinfection, and a reusable PPE protocol using a double-hit process

Derraik

Anderson

Connelly

et al. 2020

Preprint

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In the COVID-19 pandemic caused by SARS-CoV-2, hospitals are stretched beyond capacity. There are widespread reports of dwindling supplies of personal protective equipment (PPE), which are paramount to protect frontline medical/nursing staff and to minimize further spread of the virus. We carried out a rapid review to summarize the existing evidence on SARS-CoV-2 survivorship and methods to disinfect PPE gear, particularly N95 filtering facepiece respirators (FFR). In the absence of data on SARS-CoV-2, we focused on the sister virus SARS-CoV-1. We propose a two-step disinfection process, which is conservative in the absence of robust evidence on SARS-CoV-2. This disinfection protocol is based on an initial storage of PPE for ≥4 days, followed by ultraviolet light (UVC), dry heat treatment, or chemical disinfection. Importantly, each of the two steps is based on independent disinfection mechanisms, so that our proposed protocol is a multiplicative system, maximising the efficacy of our disinfection process. This method could be rapidly implemented in other healthcare settings, while testing of each method is undertaken, increasing the frontline supply of PPE, and avoiding many of the upstream issues of supply chain disruption currently being faced.

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“…Additionally, the objects should be clean prior to ultraviolet C radiation as organic material can absorb the radiation and block the reflection. It can be potentially hazardous if not used properly as per the protocol [ 55 ]. Currently, the usage of UV-C on SARS CoV-2 has not been estimated.…”

Section: Dental Radiology and Covid-19mentioning

confidence: 99%

Recommendations, Practices and Infrastructural Model for the Dental Radiology Set-up in Clinical and Academic Institutions in the COVID-19 Era

Srivastava

Shrivastava

et al. 2020

Biology

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The pandemic of Coronavirus disease (COVID-19) has emerged as a global catastrophe that is plaguing mankind. In the past eight months since the world discovered about COVID-19, we learned a lot about server acute respiratory syndrome coronavirus 2 (SARS CoV-2) and perhaps there is much more to discover and understand about the virus. With the current understanding of the disease, we assume it will remain in an active state of transmission and progression among the community for a long time. Thus, it is advisable to adopt the disease’s prevention protocol in our daily and work routine. During this pandemic patient requiring dental treatment cannot be neglected and the role of dental imaging is crucial in delivering treatment. Hence, this article attempts to provide an evidence-based compilation about the mode of transmission and clinical features of COVID-19. It also throws light on the potential source of disease transmission in the dental radiology setting. In addition, it suggests preventive measures to curb the infection and infrastructural model of the clinical setting that will assist in achieving control over the disease transmission. This article intends to project a strategy about protocols, infrastructure, and daily activities in a dental radiology office that institutions can adopt with modifications according to their local scenario.

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Ultraviolet-C decontamination of a hospital room: Amount of UV light needed

Cited by 93 publications

References 20 publications

Rapid Review of SARS-CoV-1 and SARS-CoV-2 Viability, Susceptibility to Treatment, and the Disinfection and Reuse of PPE, Particularly Filtering Facepiece Respirators

Rapid Review of SARS-CoV-1 and SARS-CoV-2 Viability, Susceptibility to Treatment, and the Disinfection and Reuse of PPE, Particularly Filtering Facepiece Respirators

Rapid evidence summary on SARS-CoV-2 survivorship and disinfection, and a reusable PPE protocol using a double-hit process

Recommendations, Practices and Infrastructural Model for the Dental Radiology Set-up in Clinical and Academic Institutions in the COVID-19 Era

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