Umbilical cord and visceral hemangiomas diagnosed in the neonatal period

Abstract

Background:Umbilical cord hemangioma is very rare and may not be detected prenatally. However, it should be considered in differential diagnosis with other umbilical masses because it can cause significant morbidity.Methods:We report the case of a newborn referred with suspected omphalitis and umbilical hernia.Results:Physical examination showed an irreducible umbilical tumor, the size of olive, with dubious secretion. The initial suspected diagnosis was urachal or omphalomesenteric duct remnants. Abdominal ultrasound and magnetic resonance imaging showed an umbilical and a mesenteric mass. Tumor markers were negative. A definitive diagnosis of umbilical cord and intestinal hemangioma was established after surgical excision and histologic examination of the umbilical mass. Propranolol was prescribed due to the extent of the intestinal lesion.Conclusion:This report highlights the diagnostic challenges of hemangiomas in unusual locations. Apart from the rarity of these tumors, few tests are available to guide diagnosis, and surgery and histologic examination are generally required for a definitive diagnosis. Finally, it is essential to rule out associated malformations and hemangiomas in other locations.

Changing Course of an Umbilical Cord Mass - Chasing the Diagnosis of Angiomyxoma

“…While no specific syndromic or genetic associations with umbilical cord angiomyxoma have been established thus far, it has rarely been reported to occur simultaneously with other congenital anomalies including cardiovascular anomaly, gastrointestinal malformation, vascular malformations of the skin, and hemangiomas of the liver, intestine, other intraabdominal organs, abdominal wall, and vulva. 1,7,11 Thus, careful physical exam and imaging, as in this case, are important to rule out other existing anomalies. The only congenital anomaly in this case was megameatus, reported once before in a neonate with cord angiomyxoma.…”

Hemangioma of the umbilical cord: A case report on a rare entity

“…No association between HUM and maternal age, race, gravidity, or gender have been reported 3 . The differential diagnoses involve hematomas, varicose veins, aneurysms, omphalomesenteric duct cysts, allantoic cysts, teratomas of the umbilical cord, placental masses, abdominal wall defects, and metastatic neuroblastoma 2,4 …”

“…Hemangiomas emerge from endothelial cells of the umbilical vessels particularly the umbilical arteries. 2 Their etiology, physiopathology, and pathways of…”

A unique case of a newborn with a hemangioma on the omphalocele sac

“…Increased levels of AFP can be seen in either umbilical cord hemangioma cases or in patients with omphalocele. 6 Mass lesions of the umbilical cord may cause circulatory collapse due to stenosis, thrombosis and torsion of the umbilical vessels via compression of the mass. This process may cause intrauterine growth retardation, non-immune hydrops fetalis and even intrauterine fetal death.…”