Umbilical endosalpingiosis: a case report

Abstract

IntroductionEndosalpingiosis describes the ectopic growth of Fallopian tube epithelium. Pathology confirms the presence of a tube-like epithelium containing three types of cells: ciliated, columnar cells; non-ciliated, columnar secretory mucous cells; and intercalary cells.We report the case of a woman with umbilical endosalpingiosis and examine the nature and characteristics of cutaneous endosalpingiosis by reviewing and combining the other four cases existing in the international literature.Case presentationA 50-year-old Caucasian, Greek woman presented with a pale brown nodule in her umbilicus. The nodule was asymptomatic, with no cyclical discomfort or variation in size. Her personal medical, surgical and gynecologic history was uneventful. An excision within healthy margins was performed under local anesthesia. A cystic formation measuring 2.7×1.7×1 cm was removed. Histological examination confirmed umbilical endosalpingiosis.ConclusionsUmbilical endosalpingiosis is a very rare manifestation of the non-neoplasmatic disorders of the Müllerian system. It appears with cyclic symptoms of pain and swelling of the umbilicus, but not always. The disease is diagnosed using pathologic findings and surgical excision is the definitive treatment.

Cutaneous Inguinal Scar Endosalpingiosis and Endometriosis

“…16,18,25,31,37,38,45,52 In the previously reported cases, the maximum diameter of the lesion with endometriosis ranged from less than 1 cm 4,9,13,21,35,52,54,56,57 to 9 cm 57 (average diameter was 2 cm), and in cases of endosalpingiosis, it spanned from 5 mm 61 to 2.7 cm. 1 In our case, the fragment in which endometriosis and endosalpingiosis were simultaneously found was 4 cm in its maximum diameter.…”

“…1,[61][62][63] The histopathological diagnosis of endometriosis is usually straightforward, but the presence of metaplasia and especially reactive atypia and decidual changes in glandular and stromal component can put some doubt on the diagnosis. The main differential diagnoses in the presence of decidual changes include trophoblastic neoplasia and mesothelioma.…”

“…On gross examination, differential diagnosis of cutaneous endometriosis or endosalpingiosis includes incisional hernia, lipoma, dermoid cyst, abscess, keloid, melanoma, suture granuloma, etc. 1,19,57 Other examination techniques that have been used include the ultrasound examination 39,42,44,47,52,57 or dermoscopy. 26,45 Laboratory tests for tumor markers may or may not show elevated levels of CA 19-9 and CA 125.…”

Tumor-like cystic endosalpingiosis in the myometrium: a case report and a review of the literature

“…many extragenital locations have been reported in the literature such as peritoneum, subperitoneal tissue, colon, appendix, umbilicus, and lymph nodes (2,4). The examples of tumor-like cystic endosalpingiosis were localized to the female pelvis and most of those cases were reported to be derived from the serosal surface of the uterus and the ovary (1,6-11).…”

“…It is derived from the mullerian system and is seen in the pelvic and lower abdominal peritoneum. Colon, bladder, appendix, paraaortic and pelvic lymph nodes are the sites specified in the case reports (2)(3)(4). Patients are almost always asymptomatic and it very rarely presents as a large cystic mass known as florid cystic endosalpingiosis (5).…”