Un consenso latinoamericano sobre el síndrome del intestino irritable

Valenzuela, Jorge; Alvarado, Jaime; Cohen, Henry; Damiao, Aderson O.; Francisconi, Carlos Fernando de Magalhães; Frugone, L.; González, Juan Carlos; Hernández, Alan Felipe Ovalle; Iade, Beatriz; Lopes, M. H. I.; Latorre, R; Prado, Julio César Acosta; Moraes-Filho, P.; Schmulson, Max; Soifer, Luis; Valdovinos, Miguel A.; Vesco, E.; Zalar, Alberto

doi:10.1016/s0210-5705(03)70470-1

Cited by 27 publications

(10 citation statements)

References 105 publications

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“…In two large clinical trials, 2 weeks of treatment with rifaximin (550 mg, three times daily) in patients with nonconstipated IBS resulted in significantly more patients reporting adequate relief of global IBS symptoms and bloating during the first 4 weeks of follow-up. 14 After completing the pilot study presented herein, we are now planning the primary study that will incorporate biopsy culture into the investigation methods in order to investigate the role of H. pylori in the development of IBS.…”

Section: Discussionmentioning

confidence: 99%

H. Pylori Infection is Associated with Development of Irritable Bowel Syndrome

2016

JERP

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Background/Objectives: The role of Helicobacter pylori in the pathogenesis of irritable bowel syndrome (IBS) was investigated in 38 subjects, including 16 males (42%) and 22 females (58%), all of who had been diagnosed with IBS but showed no improvement in response to treatment. Methods: Colonoscopy, biopsy and rapid urease test (CLO-test). Results: Nineteen patients were H. pylori-positive (50%) and 19 were H. pylori-negative (50%). One patient in this study previously presented colonic carcinoma. Conclusions: All H. pylori-positive patients received treatment and showed improvement, including the patient with colonic carcinoma. Initially, the carcinoma presented 99% of stenosis, but after one month of treatment the stenosis had decreased to 50%. As a result of this investigation, we consider that the presence of H. pylori in the colonic mucosa is another important co-factor in the pathogenesis of IBS that should also be considered in the development of colonic carcinoma.

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Section: Discussionmentioning

confidence: 99%

H. Pylori Infection is Associated with Development of Irritable Bowel Syndrome

2016

JERP

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“…Para la determinación del tamaño de muestra se utilizó la formula estadística para estudios correlaciónales. De acuerdo con referencias previas Valenzuela et al 9 se tuvo los siguientes datos prevalencia de 14,9%, nivel de confianza de 95%, con un error estimado 5%. Al realizar los cálculos se encontró que la población en estudio estuvo constituida por 195 pacientes.…”

Section: Materiales Y Metodosunclassified

Association between Irritable Bowel Syndrome and anxiety and depression in patients treated at The Regional Teaching Hospital of Trujillo

Mariños-Llajaruna¹,

Chafloque-Chafloque²

2019

rmt

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Artículo Original Asociación entre el Síndrome de Intestino Irritable y la ansiedad y depresión en pacientes atendidos en el Hospital Regional Docente de Trujillo Association between Irritable Bowel Syndrome and anxiety and depression in patients treated at The Regional Teaching Hospital of Trujillo SUMMARY Introduction: Irritable bowel syndrome (IBS) is a functional disease with episodes of exacerbation and remission of symptoms associated with alterations in motility and gastrointestinal sensitivity. Objective: to determine if there is an association between irritable bowel syndrome and anxiety and depression in outpatients. Material and methods: a correlational study was carried out that included 195 medical records of patients diagnosed with Irritable Bowel Syndrome (IBS) treated at the Gastroenterology Service of the Hospital Regional Docente de Trujillo (HRDT)-Peru, between January 2014 and December 2016. Results: Anxiety occurred in 93.3% of the patients with predominance of moderate anxiety followed by mild anxiety. In fact, there is a positive association between the degree of anxiety and the presence of IBS. (X 2 = 8.5557 p = 0.0358). On the other hand, depression occurred in 88.7% of the patients, prevailing mild depression followed by moderate depression; indeed, there is a positive association between the degree of depression and the presence of IBS. (X 2 = 9.1396 p = 0.0275). Conclusions: there is a positive association between irritable bowel syndrome and anxiety and depression in adult patients.

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“…En Latinoamérica se considera que tiene una prevalencia de 9% a 18% 3,4 . Además, es el primer motivo de consulta al gastroenterólogo y está entre los diagnósticos más comunes en medicina general 5 .…”

Section: N V E S T I G a C I ó Nunclassified

“…En el año 2004 se publicó el Consenso Latinoamericano (LATAM) sobre el SII, planteando el abordaje diagnóstico y tratamiento de este trastorno en nuestra región 3,10 . Según este Consenso, el escrutinio diagnóstico debe limitarse a ciertas pruebas de laboratorio (Tabla 1) y se debe realizar colonoscopia ante signos de alarma (pérdida de peso, hemorragia, anemia, fiebre, historia familiar de cáncer de colon o enfermedad inflamatoria intestinal), inicio de síntomas >50 años o cambio en el patrón de los síntomas 10 .…”

Section: N V E S T I G a C I ó Nunclassified

“…Con la hipótesis de que la información de una colonoscopia negativa puede mejorar la calidad de vida al tranquilizar al paciente con SII, Spiegel y cols 23 realizaron un estudio en 458 pacientes con SII a quienes se les aplicó un cuestionario y se relacionó con el antecedente de colonoscopia, no encontrando asociación entre una colonoscopia negativa y la tranquilidad del paciente o una mejor calidad de vida 23 . Nosotros hemos demostrado que aun en el caso de que esté indicado solicitar colonoscopia, el ahorro económico sería mayor de 60% según las recomendaciones del Consenso LATAM 3,10 .…”

Section: N V E S T I G a C I ó Nunclassified

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