Un siglo de barbitúricos en neurología

López-Muñoz, Francisco; Ucha-Udabe, R.; González, Cecilio Álamo

doi:10.33588/rn.3908.2004428

Cited by 11 publications

(13 citation statements)

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“…For example, (i) (paraldehyde) is widely used as a sedative, hypnotic, and anticonvulsant. 63 , 64 (vii) has been reported as one of the anticancer drug candidates. 65 However, as (iv)–(viii) are colored molecules, they may also be useful as benign dyes, e.g.…”

Section: Resultsmentioning

confidence: 99%

Pushing property limits in materials discoveryviaboundless objective-free exploration

et al. 2020

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Section: Resultsmentioning

confidence: 99%

Pushing property limits in materials discoveryviaboundless objective-free exploration

et al. 2020

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“…Thus, he is still saving hundreds of millions of lives today [ 48 ]. German organic chemist Adolf von Bayer (1835–1917, 1905 recipient of the Nobel Prize in Chemistry) synthesized barbituric acid, the parent compound of the barbiturates [ 49 , 50 ]. They are a numerous family of hypnotics that help many people overcome sleeping disorders, as well as drugs used in the treatment of epileptic seizures.…”

Section: Chemists As Children Of the Sunmentioning

confidence: 99%

Chemophobia cured by chemists: chemists as children of the Sun

Chalupa

Nesměrák

2021

Monatsh Chem

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Graphic abstract The success of chemists in the fight against COVID-19 provides us with a unique opportunity for strengthening the position of chemistry in society and suppressing chemophobia which has badly affected the image and development of chemistry over several decades. By highlighting the unique merits of chemistry in controlling infections and healing diseases, we propose developing a communication strategy “Chemists as children of the Sun”. The time is ripe for chemists to take control of the story of chemistry. We believe that chemists must help the public to see chemistry in a whole new light. Only a positive perception of chemistry and the chemical profession will secure a sufficient supply of new talents, ideas, and also financial resources for the development of this unique and irreplaceable science for humanity.

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“…This paper is the third on a series of papers concerned with the structural studies of cyclic ureas in which were presented the thermophysical and thermochemical studies of imidazolidine-2-one (1) and N,N 0 -trimethyleneurea (3) in the first paper [7] and of parabanic acid (2) in the second one [8]. As we have referred in the previous papers, the main purpose of these studies is to provide reliable data for this class of compounds that can be used both for the estimation of the thermochemical properties of related compounds that are not easy to study experimentally and also to understand the influence of steric, electrostatic, and stereo-electronic interactions produced by substituents on the thermochemical stability of these molecules.…”

Section: Introductionmentioning

confidence: 99%

“…This compound was synthesized, in 1903, by Fischer and von Mering and in the following year, the German company Bayer placed it on the market, for human use, commercialized by the name of Veronal Ò with hypnotic, sedative, and anticonvulsant properties [2]. In a medical dictionary, barbital is classified as a long-acting barbiturate that depresses most metabolic processes at high doses and it is also used in veterinary practice for central nervous system depression [3].…”

Section: Introductionmentioning

confidence: 99%