2024
DOI: 10.1101/2024.01.06.574474
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Unbiased identification of cell identity in dense mixed neural cultures

Sarah De Beuckeleer,
Tim Van De Looverbosch,
Johanna Van Den Daele
et al.

Abstract: Induced pluripotent stem cell (iPSC) technology is revolutionizing cell biology. However, the variability between individual iPSC lines and the lack of efficient technology to comprehensively characterize iPSC-derived cell types hinder its adoption in routine screening settings. To facilitate the validation of iPSC-derived cell culture composition, we have implemented an imaging assay based on cell painting and convolutional neural networks to recognize neural cell types in dense and mixed cultures with high f… Show more

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