2007
DOI: 10.1016/j.jvs.2006.11.012
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Uncommon leg ulcers in the lower extremity

Abstract: The prevalence of leg ulcers unrelated to arterial and venous disease that presented with signs and symptoms of chronic venous disease was 2.1%. Their etiology is variable, most often including vasculitis, neoplasia, metabolic disorders, infection, and other rare causes. Early identification of uncommon ulcers may facilitate timely and appropriate management.

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Cited by 42 publications
(33 citation statements)
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“…Differential diagnosis of possible causes for leg ulcers is shown in Table IV. [99][100][101] Serial VLU wound measurement and documentation are important to determine baseline markers and effect of subsequent treatment measures on healing parameters. Documentation should include number and position of ulcers on the leg.…”
Section: Clinical Evaluationmentioning
confidence: 99%
“…Differential diagnosis of possible causes for leg ulcers is shown in Table IV. [99][100][101] Serial VLU wound measurement and documentation are important to determine baseline markers and effect of subsequent treatment measures on healing parameters. Documentation should include number and position of ulcers on the leg.…”
Section: Clinical Evaluationmentioning
confidence: 99%
“…5) Nicos analyzed 710 patients with leg ulcers, and they found 2.1% of patients were due to uncommon etiology unrelated to venous or arterial pathology. 6) Their etiology is variable; Mostly vasculitis, neoplasia and metabolic disorders, but only 0.4% of patients shows infection. Mycobacterium infection should be the rarest infection for a leg ulcer.…”
Section: Discussionmentioning
confidence: 99%
“…The factors considered to influencing blood quantity were absence of pedal pulses and ankle brachial index of less than 0.9 or ankle peak systolic velocity of <75 cm/s [7][8][9] . Associated comorbidities taken into consideration included both systemic and regional conditions likely to impair wound healing or impede interventional measures, as follows: systemic diseases, such as heart failure (congestive or ischemic); chronic renal failure; and autoimmune collagen likely to cause vasculitis such as rheumatoid arthritis, systemic lupus, scleroderma, and non-specific arteritis [10][11][12][13][14] . The regional diseases that were considered in this category were conditions involving the limbs such as chronic lymphedema and chronic venous insufficiency.…”
Section: Introductionmentioning
confidence: 99%