2018
DOI: 10.23938/assn.0125
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Uncomplicated urinary tract infections. Antimicrobial susceptibility study in Navarre

Abstract: E. coli continues to be the most frequent microorganism in community-acquired UTI with a rate of sensitivity to fosfomycin and nitrofurantoin above 95%. The empirical treatment of UTI in our environment should not include amoxicillin, amoxicillin-clavulanic acid, trimethoprim-sulfamethoxazole or quinolones. Fosfomycin may be empirically used in the treatment of uncomplicated cystitis in men younger than 15 years and in women under 65 years, and nitrofurantoin may be used empirically in women under 65 years.

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Cited by 11 publications
(4 citation statements)
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“…Unfortunately, the Spanish National Hospital Discharge Database (SNHDD) does not include information on the antibiotic sensitivities of the organisms. In Spain like in other countries, antimicrobial resistance in common urinary pathogens is increasing at an alarming rate, as a result of the overuse and misuse of antibiotics [ 43 , 44 , 45 ]. The most recent Spanish paper reported that for E. coli , which continues to be the most frequent microorganism in UTIs, the sensitivity to amoxicillin, amoxicillin-clavulanic acid, trimethoprim-sulfamethoxazole, or quinolones has increased over the last years while the rate of sensitivity to fosfomycin and nitrofurantoin remained stable and above 95%.…”
Section: Discussionmentioning
confidence: 99%
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“…Unfortunately, the Spanish National Hospital Discharge Database (SNHDD) does not include information on the antibiotic sensitivities of the organisms. In Spain like in other countries, antimicrobial resistance in common urinary pathogens is increasing at an alarming rate, as a result of the overuse and misuse of antibiotics [ 43 , 44 , 45 ]. The most recent Spanish paper reported that for E. coli , which continues to be the most frequent microorganism in UTIs, the sensitivity to amoxicillin, amoxicillin-clavulanic acid, trimethoprim-sulfamethoxazole, or quinolones has increased over the last years while the rate of sensitivity to fosfomycin and nitrofurantoin remained stable and above 95%.…”
Section: Discussionmentioning
confidence: 99%
“…The most recent Spanish paper reported that for E. coli , which continues to be the most frequent microorganism in UTIs, the sensitivity to amoxicillin, amoxicillin-clavulanic acid, trimethoprim-sulfamethoxazole, or quinolones has increased over the last years while the rate of sensitivity to fosfomycin and nitrofurantoin remained stable and above 95%. The non-sensitivities were higher in men and as age increased with 6% of E. coli identified as producers of extended-spectrum beta-lactamases [ 43 , 44 , 45 ].…”
Section: Discussionmentioning
confidence: 99%
“…Aunque las ITU son más frecuentes en mujeres, las no sensibilidades lo son en el sexo masculino, tanto en el estudio previo de este grupo de trabajo 8 como en el publicado por Aguinaga et al 16 . Las no sensibilidades también se incrementan con la edad, tal como también observaron Guneysel O et al 17 , que encontraron mayores resistencias a cefpodoxima, amoxicilina/ácido clavulánico y ciprofloxacino en mayores de 50 años de edad; y Chervet et al 18 , que comunicaron mayores tasas de enterobacterias productoras de BLEE en ITU comunitarias asociadas con la edad avanzada como factor de riesgo.…”
Section: Discussionunclassified
“…UU., donde son consideradas como fármacos de primera elección, en la mayoría de los países 13 , 22 . Aguinaga et al 16 también recomiendan la fosfomicina de forma empírica en varones menores de 15 años. En varones mayores de 15 años en nuestra zona, donde las resistencias a ciprofloxacino, amoxicilina/ácido clavulánico y cotrimoxazol son muy elevadas en varones (superiores al 20%), el tratamiento empírico podría hacerse con una cefalosporina de tercera generación oral 23 tras la recogida de muestra de orina para cultivo y antibiograma.…”
Section: Discussionunclassified