An authentication code (A-code) is a two-party message authentication code in the information-theoretic security setting. One of the variants of A-codes is a multi-receiver authentication code (MRA-code), where there are a single sender and multiple receivers and the sender can create a single authenticator so that all receivers accepts it unless it is maliciously modified. In this paper, we introduce a multi-designated receiver authentication code (MDRA-code) with information-theoretic security as an extension of MRA-codes. The purpose of MDRA-codes is to securely transmit a message via a broadcast channel from a single sender to an arbitrary subset of multiple receivers that have been designated by the sender, and only the receivers in the subset (i.e., not all receivers) should accept the message if an adversary is absent. This paper proposes a model and security formalization of MDRA-codes, and provides constructions of MDRA-codes.