Diabetes is a metabolic disease that is often is associated with different systemic manifestations. Among these, there are some neurologic disorders that are the result of micro and microvascular damage. However, in some instances there can be movement disorders such as chorea and ballismus that are consequences of the direct effect of hyperglycemia in the basal ganglia, specifically in the sub thalamic nucleus. 1-3 In the next pages we present the case of a female patient with hemi chorea and hemiballism as the first manifestation of diabetes mellitus, conducting a discussion on the clinical manifestations, the pathophysiology, the radiological findings and the therapeutic options. Our aim is to point out the importance of an early detection of this reversible and treatable condition.