2024
DOI: 10.21203/rs.3.rs-4549293/v1
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Uncovering Naringin’s Anticancer Mechanisms in Glioblastoma via Molecular Docking and Network Pharmacology Approaches

Arunraj Tharamelveliyil Rajendran,
Gupta Dheeraj Rajesh,
Harsha Ashtekar
et al.

Abstract: Naringin, a flavonoid, exhibits diverse therapeutic properties and has been proven to exert cytotoxic effects on cancer cells. Nevertheless, the precise mechanism of naringin maintaining its cytotoxic effect on glioblastoma (GBM) remains unknown. Thus, the current study aimed to establish a plausible cellular mechanism for Naringin's inhibition of GBM. We employed various system biology techniques to forecast the primary targets, including gene ontology and cluster analysis, KEGG enrichment pathway estimation… Show more

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