Under pressure: an ocular complication of oral corticosteroid therapy: Table 1

Abstract

SummaryWe describe the case of a patient with steroid sensitive nephrotic syndrome who is admitted with headaches, eye pain and reduced visual acuity. Despite thorough investigation no cause for the pain is identified. On a subsequent admission for recurrence of her symptoms her intraocular pressures are measured, which are markedly raised. Immediate medical treatment, as well as prompt weaning of her steroid therapy avoided the need for trabeculectomy surgery. We review this case and the literature surrounding this condition in children. BACKGROUND

Republished: Severe acute ocular hypertension following pulsed methylprednisolone for juvenile idiopathic arthritis

“…Our case is noteworthy for several reasons: the severity of the ocular hypertension, the rapid speed of onset following the administration of intravenous steroids and due to its asymptomatic nature, being discovered almost incidentally. A previous published case described a patient with symptoms (headaches, eye pain, reduced visual acuity),5 while another described the onset following several months of therapy,6 but none described such markedly raised pressures in an asymptomatic patient.…”

Corticosteroids in ophthalmology: drug delivery innovations, pharmacology, clinical applications, and future perspectives

“…Patients with elevated IOP may have symptoms of headache, eye pain and reduced visual acuity [260]. The first report of increased IOP induced by locally administered corticosteroids was described by Francois [14].…”