2019
DOI: 10.1523/jneurosci.0742-19.2019
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Under the Mind's Hood: What We Have Learned by Watching the Brain at Work

Abstract: Imagine you were asked to investigate the workings of an engine, but to do so without ever opening the hood. Now imagine the engine fueled the human mind. This is the challenge faced by cognitive neuroscientists worldwide aiming to understand the neural bases of our psychological functions. Luckily, human ingenuity comes to the rescue.

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Cited by 14 publications
(10 citation statements)
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References 211 publications
(272 reference statements)
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“…In particular, activity in the left inferior posterior parietal cortex and associated frontal regions has been repeatedly noted (Coull et al., 2016; Coull & Nobre, 2008; Nobre & Rohenkohl, 2014). Neuroimaging, however, has limitations in defining the functional specialization of brain areas (see Nobre & van Ede, 2020). For example, it can be difficult to separate brain areas involved in generating temporal expectations from those that are modulated as a consequence.…”
Section: Introductionmentioning
confidence: 99%
“…In particular, activity in the left inferior posterior parietal cortex and associated frontal regions has been repeatedly noted (Coull et al., 2016; Coull & Nobre, 2008; Nobre & Rohenkohl, 2014). Neuroimaging, however, has limitations in defining the functional specialization of brain areas (see Nobre & van Ede, 2020). For example, it can be difficult to separate brain areas involved in generating temporal expectations from those that are modulated as a consequence.…”
Section: Introductionmentioning
confidence: 99%
“…Then, the amplitude envelope of each of the IMFs is decomposed into a set of amplitude modulated IMFs (IMFs AM ), constituting the second layer. Although HHSA can go through multiple iterations until the amplitude functions bear no more cyclic characteristics in the envelopes, in practice only two iterations are performed [6,33,35,[37][38][39].…”
Section: Introductionmentioning
confidence: 99%
“…On the other hand, the AM frequency represents the slow-changing inter-mode frequency variations; it can be used to analyze interactions between IMFs FM [7]. Although the HHSA method can go through multiple iterations until it bears no more cyclic characteristics, only two iterations are performed in practice [7,41,43,[46][47][48].…”
Section: Introductionmentioning
confidence: 99%
“…In sum, understanding the hippocampal-cortical dynamics supporting memory recall has been hindered by the temporal ambiguities inherent in fMRI. We thus capitalised on the enhanced temporal resolution afforded by human electrophysiological recordings (Nobre and van Ede, 2020;Rugg and Curran, 2007;Staresina and Wimber, 2019), employing the same cued recall paradigm ( Figure 1) across three studies, ranging from single-neuron to whole-brain recordings. First, we recorded intracranial Electroencephalography (iEEG) from hippocampus as well as extrahippocampal sites in pre-surgical epilepsy patients, including a case with hippocampal single unit microwire recordings.…”
Section: Introductionmentioning
confidence: 99%