The rationale to perform left ventriculography at the time of cardiac catheterization has been little studied. The technique and frequency of use of left ventriculography vary by geographic regions, institutions, and individuals. Despite the recent publication of guidelines and appropriate use criteria for coronary angiography, revascularization, and noninvasive imaging, to date there have been no specific guidelines on the performance of left ventriculography. When left ventriculography is performed, proper technique must be used to generate high quality data which can direct patient management. The decision to perform left ventriculography in place of, or in addition to, other forms of ventricular assessment should be made taking into account the clinical context and the type of information each study provides. This paper attempts to show the role of left ventriculography at the time of coronary angiography or left heart catheterization. The recommendations in this document are not formal guidelines but are based on the consensus of this writing group. These recommendations should be tested through clinical research studies. Until such studies are performed, the writing group believes that adoption of these recommendations will lead to a more standardized application of ventriculography and improve the quality of care provided to cardiac patients. Catheterization and Cardiovascular Interventions 85:181-191 (2015) While guidelines and appropriate use criteria (AUC) have addressed the indications for left heart catheterization associated with coronary angiography [2] and to evaluate heart failure [3], they have not addressed the role of left ventriculography. This document attempts to fill that void. It deals only with left ventriculography (invasive imaging of the left ventricle with contrast injection) and does not address left heart catheterization (catheter placement in the left ventricle, usually to assess pressures).Currently, there are no specific guidelines on the performance of left ventriculography at the time of coronary angiography or left heart catheterization. Recent AUC for diagnostic catheterization define clinical scenarios where coronary angiography and/or left heart catheterization is appropriate, uncertain, or inappropriate, but the decision to perform ventriculography is left to the discretion of the operator. Patel et al. have suggested clinical scenarios where cardiac catheterization (defined as including coronary angiography, left heart catheterization, and left ventriculography) is an appropriate imaging modality in the evaluation of a possible ischemic etiology of heart failure [3]. They did not define specifically the appropriateness of left ventriculography alone, particularly when other measurements of LV systolic function are available.Regional variation in the performance of ventriculography in the United States has been noted by several authors. Joffe et al.