Undernutrition increased the risk of loss to follow-up among adults living with HIV on ART in Northwest Ethiopia: a retrospective cohort study

Alebel, Animut; Sibbritt, David; Petrucka, Pammla; Demant, Daniel

doi:10.1038/s41598-022-27077-y

Cited by 3 publications

(1 citation statement)

References 39 publications

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“…This discovery is consistent with previous research undertaken in Tanzania and Northwest Ethiopia, which also presents similar patterns. 31,32 This association can be attributed to the improved immune function that accompanies longer ART treatment, which reduces diarrhea and vomiting and reduces the risk of opportunistic infections. Therefore, patients may experience enhanced appetite, increase dietary intake, and improve nutritional status.…”

Section: Discussionmentioning

confidence: 99%

Magnitude and Factors Associated with Undernutrition Among Children on Antiretroviral Therapy in the East Wollega Zone, Western Ethiopia

Shibiru,

Arulandhu

2023

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Background: Insufficient food intake and infectious diseases cause undernutrition. Undernutrition in children is a severe public health issue globally, especially in low-resource areas. Among the most vulnerable to these challenges, children affected by HIV/AIDS in Ethiopia are at risk of undernutrition, which links to increased child morbidity and mortality. Despite the significance of the issues, there is no report in the East Wollega Zone of Ethiopia. Therefore, the present study aims to assess the magnitude and determinants of undernutrition among children receiving antiretroviral therapy (ART) in the east Wollega zone of Ethiopia. Methods: From June to July 2022, a survey was carried out in the East Wollega Zone of Ethiopia to collect the data. The study sample comprised 380 children aged ≤ 15 years who were being treated with ART. A systematic questionnaire and anthropometric measurements were used to collect the data. Epi data 3.1 and SPSS version 26.0 was used for the input data, and data analysis respectively. The relationship between independent variables and undernutrition was identified using logistic regression analysis. Results:The study revealed that the magnitude of undernutrition (WFH <-2 Z-score) was 36.8% with a 95% CI (32.1, 41.8). Having acute disease two weeks before the survey (AOR = 5.82, 95% CI: 2.86, 11.84), CD4 level (AOR = 1.85, 95% CI: 1.06, 3.25), treating water at home (AOR = 3.30, 95% CI: 1.8, 6.05), duration of follow-up (AOR = 1.97, 95% CI: 1.11, 3.47), food insecurity (AOR = 3.55, 95% CI: 2.03, 6.19), and latrine unavailability (AOR = 2.73, 95% CI: 1.39, 5.36) were statistically significant associations with undernutrition among children with ART. Conclusions: The magnitude of undernutrition is a significant problem among pediatric populations affected by HIV/AIDS in the eastern Wollega zone of Ethiopia. The factors associated with undernutrition include acute disease, low CD4 levels, non-treated water at home, duration of follow-up, food insecurity, and latrine unavailability. Public health facilities should implement measures to address these factors to improve the dietary status of children living with HIV/AIDS.

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Section: Discussionmentioning

confidence: 99%

Magnitude and Factors Associated with Undernutrition Among Children on Antiretroviral Therapy in the East Wollega Zone, Western Ethiopia

Shibiru,

Arulandhu

2023

Preprint

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Case-control study on challenges in loss of follow-up care and the limitations in the reach of HIV policies for women

Tizianel Aguilar,

Lamperti Thomazi,

Acosta

et al. 2024

Int J STD AIDS

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Introduction HIV has transitioned from a devastating 1980s epidemic to a manageable chronic condition with antiretroviral therapy. In Brazil, challenges persist, including high detection rates and loss of medical follow-up among people living with HIV/AIDS (PLHIV). Adherence, engagement, and avoiding loss to follow-up are critical for effective HIV/AIDS prevention and care. Objectives This case-control study within longitudinal research on PLHIV linkage and retention in Porto Alegre aims to analyze factors associated with treatment abandonment. Methods The study, based on patients from the Therapeutic Care Service for HIV and AIDS at Sanatorio Partenon Hospital, involved 360 PLHIV in a retention and linkage outpatient clinic. Results Risk factors for loss to follow-up include cisgender women, diagnosis between 1991 and 2005, and non-adherence to antiretroviral treatment (ART). Conversely, cisgender men, diagnosis between 2015 and 2023, and good ART adherence were protective factors. Conclusion Gender disparities and ART non-adherence pose significant challenges in comprehensive PLHIV care. Cisgender women diagnosed before 2005 face higher risk, while cisgender men diagnosed after 2015 with good ART adherence are more protected, influencing care and prevention strategies for PLHIV.

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Barriers Contributing to Loss to Follow-up among HIV-patients in Limpopo Province, South Africa: Patients’ and Nurses’ Perspectives

Modipane,

Khoza,

Ingersoll

2023

TOPHJ

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Background: Antiretroviral therapy is a lifelong commitment that requires patients to adhere to their daily medication dose schedules and make frequent visits to health services for their care. People living with HIV can live healthy long lives when retained on antiretroviral therapy. Retention in care has been identified as the benchmark in the HIV Care Continuum, where most people living with HIV fail. Interventions are urgently needed to address this benchmark to achieve the worldwide 95-95-95 goals. Despite the South African government`s efforts to expand access to antiretroviral therapy services from urban centers to resource-constrained rural communities, there were 140,000 HIV- related deaths in 2014 and 85,796 HIV- related deaths in 2021. Patients have become lost to follow-up, putting their health and that of their communities at risk. Moreover, the loss of follow-up care among HIV-positive people who are on antiretroviral treatment continues to be a significant problem. The study determined barriers contributing to the Loss of follow-up rates among people living with HIV. Methods: A qualitative research study was conducted; Non-probability purposive sampling was used to select eight nurses from clinics with the highest and lowest loss-to-follow-up rates. The probability systematic sampling method was used to select patients from the selected clinics. Data were collected through semi-structured interviews, and content analysis was used to analyse the data. Results: Patients’ and nurses’ perspectives on barriers contributing to the loss of follow-up among people living with HIV included lack of confidentiality, lack of understanding of antiretroviral treatment, patients’ self-transfer, and feeling better physically. Conclusion: Understanding the reasons for the Loss of follow-up could inform the development of retention in care interventions for Limpopo province. The study can be most beneficial with HIV education, skills building, and outreach programme strategies; this will, in turn, increase the knowledge needed to better attract and retain HIV-positive patients in healthcare settings.

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Undernutrition increased the risk of loss to follow-up among adults living with HIV on ART in Northwest Ethiopia: a retrospective cohort study

Cited by 3 publications

References 39 publications

Magnitude and Factors Associated with Undernutrition Among Children on Antiretroviral Therapy in the East Wollega Zone, Western Ethiopia

Magnitude and Factors Associated with Undernutrition Among Children on Antiretroviral Therapy in the East Wollega Zone, Western Ethiopia

Case-control study on challenges in loss of follow-up care and the limitations in the reach of HIV policies for women

Barriers Contributing to Loss to Follow-up among HIV-patients in Limpopo Province, South Africa: Patients’ and Nurses’ Perspectives

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