Understanding adverse drug-related emergency department visits: development of a conceptual model through a systematic review

Jatau, Abubakar Ibrahim; Shitu, Zayyanu; Khalid, Garba M.; Yunusa, Ismaeel; Awaisu, Ahmed

doi:10.1177/2042098619852552

Cited by 8 publications

(9 citation statements)

References 66 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Nigerian borders should be well protected with surveillance activities by responsible agencies. (2)Applying the conceptual model for understanding adverse drug events in the community [ 48 ]. Intervention measures based on Group-focused Cognitive Behavioral Health Education Program (GCBHEP) should be adopted to improve awareness and behavioral change [ 49 ].…”

Section: Resultsmentioning

confidence: 99%

“…Intervention measures based on Group-focused Cognitive Behavioral Health Education Program (GCBHEP) should be adopted to improve awareness and behavioral change [ 49 ]. Based on the model, other community-based education awareness in the form of mass campaigns through media houses both print and electronic, adverts, flyers, banners, radio jingles, lectures and other programs in religious places and public functions should be created and sustained [ 48 ]. (3)Secondary school-based programs aimed at encouraging healthy practices and lifestyle among adolescents would help to prevent substance use.…”

Section: Resultsmentioning

confidence: 99%

See 1 more Smart Citation

The Burden of Drug Abuse in Nigeria: A Scoping Review of Epidemiological Studies and Drug Laws

Jatau¹,

Sha’aban²,

Gulma

et al. 2021

Public Health Rev

Self Cite

View full text Add to dashboard Cite

Background: The burden of drug abuse is becoming a public health concern in Nigeria. Preventive measures should include identifying the root causes of the burden for targeted intervention. We, therefore, aim to conduct a scoping review of the literature to summarize the findings of epidemiological studies on drug abuse and provisions of drug laws in Nigeria. The review also provides appropriate recommendations as interventions for prevention.Methods: We conducted a systematic search of the literature on PubMed to identify information on drug abuse and drug laws in Nigeria from the inception of the database to March 2020. Additional information was retrieved from Google Scholar, a manual search of included articles, discussion with experts on the subject matter, and gray literature. Study selection was performed using the Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) statements. Information from gray literature was assessed for quality and accuracy using the AACODS checklist (authority, accuracy, coverage, objectively, date, significance).Results: The systematic search of the literature generated 253 studies. Nine articles were obtained from other sources. After the selection process, 23 eligible studies were included for review. A prevalence of 20–40% and 20.9% of drug abuse was reported among students and youths, respectively. Commonly abused drugs include cannabis, cocaine, amphetamine, heroin, diazepam, codeine, cough syrup and tramadol. Sources where abusers obtained drugs, were pharmacies/patent medicine shops, open drug markets, drug hawkers, fellow drug abusers, friends, and drug pushers. Drug abuse was common among undergraduates and secondary school students, youths, commercial bus drivers, farmers, and sex workers. Reason for use included to increase physical performance, stress and to derive pleasure. Poor socioeconomic factors and low educational background were the common risk factors associated with drug abuse. We identified several drug laws and policies that were established under government agencies such as the National Drug Law Enforcement Agency (NDLEA), National Agency for Foods and Drugs Administration and Control (NAFDAC), Pharmacists Council of Nigeria (PCN) and a Presidential Advisory Committee.Conclusion: Findings from epidemiological studies on drug abuse in Nigeria has demonstrated that the burden of drug abuse is still high despite the existing drug laws, policies, and strategies for prevention. Measures to reduce the burden should involve the community, government, and religious bodies. Preventive measures should target the youths, the students, identified sources of the drugs, reasons and risk factors associated with drug abuse in Nigeria.

show abstract

Section: Resultsmentioning

confidence: 99%

Section: Resultsmentioning

confidence: 99%

The Burden of Drug Abuse in Nigeria: A Scoping Review of Epidemiological Studies and Drug Laws

Jatau¹,

Sha’aban²,

Gulma

et al. 2021

Public Health Rev

Self Cite

View full text Add to dashboard Cite

show abstract

“…Recently, a model for better understanding ADE-related ED visits was settled by Jatau and colleagues ( Jatau et al, 2019 ). Authors identified a lack in knowledge and clinical practice, as well as targeted interventions to improve strategies for the prevention of ADEs.…”

Section: Discussionmentioning

confidence: 99%

Risk of Hospitalization Associated with Cardiovascular Medications in the Elderly Italian Population: A Nationwide Multicenter Study in Emergency Departments

et al. 2021

View full text Add to dashboard Cite

Background: There is a significant gap in knowledge addressing cardiovascular (CV) medications safety in elderly. In this context, our purposes were to define clinical and pharmacological characteristics of outpatients’ adverse drug events (ADEs) related to CV medications leading to emergency department (ED) visits in the elderly Italian patients according to different age groups, and to evaluate the risk of hospitalization associated to ADEs in this population.Methods: A multicentre, retrospective study was performed on reports of suspected ADEs collected between 2007–2018 in 94 EDs involved in the MEREAFaPS Study. Elderly patients who experienced one or more CV medications-related ADEs leading to ED visit were selected. Patients’ characteristics, suspected (ATC classes B and C) and concomitant drugs, and ADE description were collected. Elderly patients were stratified into three age groups (65–74, 75–84, and ≥85 years) and compared to adults (18–64 years). Logistic regression analyses were used to estimate the reporting odds ratios (RORs) with 95% confidence intervals (CIs) of ADE-related hospitalization adjusting for sex, presence of two or more suspected drugs, concomitant drugs, and one or more comorbidities.Results: Among elderly, 16,926 reports of suspected ADE related to CV medications were collected, and 6,694 (39.5%) resulted in hospitalization. Patients were mostly female, Caucasians, and middle-old (75–84). 78.9% of patients were treated with only one suspected drug, and 71.9% and 47.1% reported concomitant medications and comorbidities, respectively. Compared to adults, risk of hospitalization was significantly higher for middle-old and oldest-old patients exposed to vitamin K antagonists (1.29 [1.09–1.52] and 1.56 [1.30–187]), direct thrombin inhibitors (3.41 [1.44–8.08] and 4.12 [1.67–10.17]), antiplatelets (1.51 [1.26–1.81] and 2.09 [1.71–2.57]), and beta-blockers (1.89 [1.38–2.59 and 2.31 [1.60–3.35]). Overall, a higher risk of hospitalization was observed for renin-angiotensin system inhibitors (1.32 [1.04–1.68], 1.65 [1.32–2.06], and 2.20 [1.70–2.85]), presence of two or more concomitant drugs, and concomitant conditions.Conclusion: Our real-world findings underline relevant safety aspects of CV medications in the elderly Italian population. ED clinicians must always consider the higher risk of hospitalization related to the use of CV drugs in elderly, particularly in oldest-old ones, for antiarrhythmics, beta-blocking agents, renin-angiotensin system inhibitors, antiplatelets, and anticoagulants.

show abstract

“…In addition, pharmacists ensure quality, effectiveness, and appropriate storage conditions of medications in healthcare facilities, and are actively involved in screening prescriptions for potential error and to suggest appropriate deprescription options. [4][5][6] Nigeria has a population of over 190 million people. 7 A 2018 survey has revealed that out of the total number of 21,892 registered pharmacists in the country, only 12,807 are in active professional service.…”

Section: Introductionmentioning

confidence: 99%

Assessment of occupational violence towards pharmacists at practice settings in Nigeria

Khalid¹,

Idris²,

Jatau³

et al. 2020

Pharm Pract (Granada)

Self Cite

View full text Add to dashboard Cite

Background: Occupational Violence is prevalent among healthcare workers, including pharmacists, and poses a big threat to their job satisfaction, safety, and social wellbeing. Objective: This study seeks to assess the incidents and factors associated with occupational violence towards pharmacists in Nigeria. Methods: A cross-sectional study was conducted among pharmacists practicing in Nigeria, using an online survey (Google FormTM). Occupational violence was assessed using a validated questionnaire. The survey was conducted and reported based on the Checklist for Reporting Results of Internet E-Surveys (CHERRIES). Participants were recruited by sharing the survey link via social media platforms including WhatsApp, Facebook, LinkedIn, and Twitter. Results: A total of 263 respondents returned the online questionnaire, with a completion rate of 99.2%. The prevalence of occupational violence was 92.7% (95% CI, 90 to 96). Violent events occurred among 48.7% of pharmacists with at least six years of experience, and 68.4% of hospital pharmacists. The commonly reported factors associated with the violence include long waiting times in the pharmacy (36.5%), refusal to fulfil aggressor’s demands (22.1%), and counseling/poor communication (21.7%). Events related to verbal abuse were reported among 95% of the participants. The prevalence of violence was significantly higher among hospital pharmacists, compared with those practicing in administration/regulatory, and in community pharmacies (chi-square=10.213 (2); p=0.006). Similarly, physical aggression was higher among hospital pharmacists (chi-square=10.646 (2), p = 0.005). Conclusions: The prevalence of occupational violence towards pharmacists practicing in Nigeria appeared to be high. Major factors associated with the violence were refusal to fulfil aggressors’ demands and frustrations due to long waiting times at pharmacy. Recommended strategies to slowdown the incidences of violence were improved pharmacists’ workforce, interprofessional harmony, and penalties against perpetrators.

show abstract

Understanding adverse drug-related emergency department visits: development of a conceptual model through a systematic review

Cited by 8 publications

References 66 publications

The Burden of Drug Abuse in Nigeria: A Scoping Review of Epidemiological Studies and Drug Laws

The Burden of Drug Abuse in Nigeria: A Scoping Review of Epidemiological Studies and Drug Laws

Risk of Hospitalization Associated with Cardiovascular Medications in the Elderly Italian Population: A Nationwide Multicenter Study in Emergency Departments

Assessment of occupational violence towards pharmacists at practice settings in Nigeria

Contact Info

Product

Resources

About