Understanding and controlling type I collagen adsorption and assembly at interfaces, and application to cell engineering

Dupont‐Gillain, Christine C.

doi:10.1016/j.colsurfb.2014.08.029

Cited by 17 publications

(7 citation statements)

References 49 publications

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“…Collagen does not express antigenicity in physiological conditions, it is completely resorbable in vivo and its physicochemical properties can be suitably controlled. Because of its unique biological and functional properties, collagen has been widely applied in food, cosmetic, base for smart hydrogels and medicine [8][9][10][11][12][13] . At the present there is wide interest in collagen as biomaterials.…”

Section: Introductionmentioning

confidence: 99%

“…At the present there is wide interest in collagen as biomaterials. It is most frequent used as hard and soft capsules, microspheres, sealants for vascular prostheses, wound dressing, drug delivery agent and three-dimensional tissue scaffold in tissue engineering 11,12,14,15 Collagen is used in tissue engineering as scaffolds in three forms. The first form is the collagen gel system 16,17 .…”

Section: Introductionmentioning

confidence: 99%

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Extraction and Characterization of Collagen from Buffalo Skin for Biomedical Applications

Rizk¹,

Mostafa²

2016

Orient. J. Chem

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Collagen is widely used for biomedical and pharmaceutical applications due to its excellent biocompatibility, biodegradability and weak antigenicity. However, applicability is limited due to its high cost and probability of disease transmission from the current sources, which are bovine and porcine. In the present study, collagen was extracted from 6 months buffalo skins as alternative save sources. Collagen was characterized by different physico-chemical techniques like ATR-FTIR, Raman, SEM, DSC and amino acids analysis. Proline and hydroxyproline contents of buffalo skin collagen were higher than those of calf skin collagen. Thermal stability of buffalo skin collagen is high with respect to that of calf skin collagen. The obtained buffalo skin collagen shows higher stiffness upon cross-linking with glutaraldehyde. Thus buffalo skin collagen can be used for fabrication of high strength bioactive sponge and sheets for medical applications, like scaffold for tissue engineering, drug delivery and wound dressing system.

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Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Extraction and Characterization of Collagen from Buffalo Skin for Biomedical Applications

Rizk¹,

Mostafa²

2016

Orient. J. Chem

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“…Many researchers have recently demonstrated the outstanding potentiality of electrospinning for the engineering of 1D polymeric biointerfaces from natural and synthetic polymers [ 180 ]. Among the biopolymers that can favour cell adhesion, collagen is a very convenient choice, since it can be easily obtained from natural sources and at low cost, being the most abundant protein in the animal kingdom, where it plays the role of the major component of extracellular matrices [ 181 ] and can be used for cells immobilization [ 182 ]. However, it is difficult to obtain oriented 1D polymeric structures that can enhance oriented cellular growth and attachment.…”

Section: 1d Polymeric Materialsmentioning

confidence: 99%

On the Interaction between 1D Materials and Living Cells

Arrabito

Aleeva

Ferrara

et al. 2020

JFB

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One-dimensional (1D) materials allow for cutting-edge applications in biology, such as single-cell bioelectronics investigations, stimulation of the cellular membrane or the cytosol, cellular capture, tissue regeneration, antibacterial action, traction force investigation, and cellular lysis among others. The extraordinary development of this research field in the last ten years has been promoted by the possibility to engineer new classes of biointerfaces that integrate 1D materials as tools to trigger reconfigurable stimuli/probes at the sub-cellular resolution, mimicking the in vivo protein fibres organization of the extracellular matrix. After a brief overview of the theoretical models relevant for a quantitative description of the 1D material/cell interface, this work offers an unprecedented review of 1D nano- and microscale materials (inorganic, organic, biomolecular) explored so far in this vibrant research field, highlighting their emerging biological applications. The correlation between each 1D material chemistry and the resulting biological response is investigated, allowing to emphasize the advantages and the issues that each class presents. Finally, current challenges and future perspectives are discussed.

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“…The brillary structure of the polymer crust can be attributed to the brillation of Col, a phenomenon commonly reported under the studied conditions. 49,55 The progressive growth of the HA/Col multilayer further opens the opportunity to tune the thickness of the biomimetic shell functionalizing the rigid PPy interface.…”

Section: Biofunctionalization Of Ppy Frameworkmentioning

confidence: 99%

Biofunctionalized and self-supported polypyrrole frameworks as nanostructured ECM-like biointerfaces

et al. 2018

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Hybrid nanobiointerfaces were designed as an original contribution to the challenge of synthesizing nanostructured biomaterials integrating a set of cell fate-determining cues, originally provided to cells by the extracellular matrix (ECM). The produced biointerfaces consist of a stiff framework of intersected polypyrrole (PPy) nanotubes supporting a soft multilayer composed of ECM-derived biomacromolecules: collagen (Col) and hyaluronic acid (HA). PPy frameworks with highly tunable characteristics were synthesized through chemical oxidative polymerization of pyrrole monomers, templated within tracketched polycarbonate (PC) membranes featuring a network of intersected nanopores. PPy interfaces with a porosity of 80%, composed of nanotubes with an average diameter ranging from 40 to 300 nm, intersecting at an angle of 90 , were shown to be self-supported. These rigid PPy nanostructured interfaces were functionalized with a self-assembling (HA/Col) multilayer deposited via a layer-by-layer process. Biofunctionalized and unmodified PPy frameworks were both shown to promote sustained cell adhesion, therefore demonstrating the cytocompatibility of the engineered matrices. Such nanobiointerfaces, combining a mechanically-stable framework of tunable dimensions with a soft biopolymeric multilayer of highly versatile nature, pave the way towards cell-instructive biomaterials able to gather a wide range of cues guiding cell behavior. The developed self-supported structures could be used as a coating or as membranes bridging different tissues.

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Understanding and controlling type I collagen adsorption and assembly at interfaces, and application to cell engineering

Cited by 17 publications

References 49 publications

Extraction and Characterization of Collagen from Buffalo Skin for Biomedical Applications

Extraction and Characterization of Collagen from Buffalo Skin for Biomedical Applications

On the Interaction between 1D Materials and Living Cells

Biofunctionalized and self-supported polypyrrole frameworks as nanostructured ECM-like biointerfaces

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