Understanding attitudes and beliefs regarding COVID-19 vaccines among transitional-aged youth with mental health concerns: a youth-led qualitative study

Artna, Erin; Abi-Jaoudé, Alexxa; Sockalingam, Sanjeev; Perry, Claire; Johnson, Andrew; Wun, Charlotte; Kozloff, Nicole; Henderson, Jo; Levinson, Andrea; Buchman, Daniel Z

doi:10.1136/bmjopen-2023-080707

Cited by 3 publications

(1 citation statement)

References 36 publications

(80 reference statements)

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“…Safety is a key factor shaping individuals’ vaccine acceptance, especially during unforeseeable public health crises. When individuals are unsure about vaccine efficacy, safety becomes their primary concern 43 . Hence, strategies addressing safety concerns and providing transparent, accurate vaccine safety information are crucial for improving vaccination attitudes and uptake rates.…”

Section: Discussionmentioning

confidence: 99%

A psychometric assessment of a novel scale for evaluating vaccination attitudes amidst a major public health crisis

Cheng,

Kong,

Xie

et al. 2024

Sci Rep

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Despite abundant scientific evidence supporting immunization benefits, vaccine hesitancy remains a significant global health concern, particularly during public health crises. Exploring public attitudes towards vaccination is crucial. This study aimed to develop and validate a tailored Public Vaccination Attitudes Scale specifically under the unique circumstances of a public health crisis. A psychometric evaluation was conducted using a cross-sectional study during the peak of a major public health crisis. The scale was developed and its psychometric properties validated using three approaches: (1) generating the item pool through literature research and focus group discussions; (2) assessing the items through expert consultation; and (3) evaluating construct validity, content validity, and internal consistency reliability through exploratory factor analysis (EFA) and confirmatory factor analysis (CFA). Data from a total of 3921 respondents were randomly divided into two subsets, one for EFA (n = 1935) and the other for CFA (n = 1986). A 22-item draft scale with five factors was created after literature research and focus group discussion. The content validity of this scale ranged between 0.88 and 1.00. EFA showed a 17-item scale with four factors (Cronbach’s α > 0.7) accounting for 68.044% of the total variance. CFA showed that the values of the fit indices, including convergent validity and discriminant validity, were excellent or acceptable. The overall Cronbach’s α was 0.874, and each factor ranged from 0.726 to 0.885. This study introduces a valuable tool for assessing vaccination attitudes during public health crises, aiding researchers, policymakers, and nurses in combating vaccine hesitancy. Emphasizing the importance of fostering vaccine acceptance, it enhances disease control during emergencies, contributing to the knowledge needed for more effective public health strategies and crisis responses

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Section: Discussionmentioning

confidence: 99%

A psychometric assessment of a novel scale for evaluating vaccination attitudes amidst a major public health crisis

Cheng,

Kong,

Xie

et al. 2024

Sci Rep

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Understanding Attitudes Toward Zoster Vaccination in the Hospital Setting: A Multidisciplinary Model to Contrast Vaccine Hesitancy in Fragile Patients. A prospective longitudinal observational study

Martinelli,

Regazzi,

Rizzo

et al. 2024

Preprint

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Introduction: The efficacy of recombinant adjuvanted vaccine (RZV) against Herpes Zoster (HZ) is universally recognized and is the only safe vaccine in immunocompromised persons and in higher-risk individuals. Higher-risk patients with primary or acquired immunodeficiencies are characterized by an increased risk of disseminated infection after HZ infection or after reactivation of HZ virus, due to their clinically fragile condition. To date, the rate of vaccination with RZV through non-hospital health services in this population does not reach optimal standards, either because of difficulties in accessing care or because of vaccine hesitancy (VH). According to the latest international guidelines, interventions to support community medicine are needed to increase vaccination coverage and to counteract VH. Methods The Fondazione Policlinico Universitario Agostino Gemelli IRCCS Hospital in Rome performed an organizational management model including the hospital and non-hospital health services (ASL Roma 1) dedicated to vaccine counseling and contrasting VH in frail patients with an indication for RZV vaccination. Multiple linear regression was used to analyze the impact of results. Results From July 2022 to July 2023, 178 patients underwent vaccine counseling and received two doses of RZV vaccine, of which, 90 responded to the recall to evaluate side effects, breakthrough HZ Infections and answered to the VAX Scale questionnaire. 34.27% were affected by HIV infection, 23% by HZ relapses or severe forms, and 21.35% by rheumatologic diseases. Total VH score tot 2.291. A statistically significant correlation was demonstrated between age/rheumatology patients/female sex and overall vaccine hesitancy. 80% and 74.44% of patients had no short-term side effects after the first and second doses, respectively. 3.33% had breakthrough HZ Infections. No patients had minor or major long-term (1 year) side effects. Comparison of responses to VAX scale in the first and recall phase, showed positive changes about VH, with differences ranging from 2.9 to 3.0 points. Conclusions This study demonstrates that a multidisciplinary approach to vaccine counseling can significantly reduce vaccine hesitancy and improve adherence among frail, high-risk patients. Trial registration: ClinicalTrials.gov ID: NCT06334861; date of registration: 2023-03-13

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Systematic Review: The Relationship Between Vaccine Hesitancy Against Covid-19 and Anxiety Disorders

BLĂNARU,

VAIDA

2024

RPSIH

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The present systematic review is a qualitative research aimed to synthesize and understand the hesitancy phenomenon of vaccination against COVID 19 for the population experiencing mental health problems, for certain various anxiety disorders. Thematic conclusions from 20 studies that observed the phenomenon of acceptance of vaccination against coronavirus for several types of population were analysed: some studies involve patients from Mental Health Care (n = 6), some are about university students (n = 3), general population with electronic records (n = 6), women from fertility centres (n = 2), refugees (n = 1) and patients with chronic conditions (n = 2). According to the findings of this systematic analysis, avoiding coronavirus vaccination is a complex phenomenon that is strongly linked to anxiety disorders. However, several factors contribute to the observed correlations, both mediating and moderating, allowing us to have a better understanding of the mechanism.

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Understanding attitudes and beliefs regarding COVID-19 vaccines among transitional-aged youth with mental health concerns: a youth-led qualitative study

Cited by 3 publications

References 36 publications

A psychometric assessment of a novel scale for evaluating vaccination attitudes amidst a major public health crisis

A psychometric assessment of a novel scale for evaluating vaccination attitudes amidst a major public health crisis

Understanding Attitudes Toward Zoster Vaccination in the Hospital Setting: A Multidisciplinary Model to Contrast Vaccine Hesitancy in Fragile Patients. A prospective longitudinal observational study

Systematic Review: The Relationship Between Vaccine Hesitancy Against Covid-19 and Anxiety Disorders

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