A decentralised, tamper-proof ledger offered by blockchain technology has the potential to revolutionise the manufacturing sector by enhancing digital rights management, supply chain management, and product monitoring and tracking. Industrial supply chains may be made more transparent, secure, and efficient with the use of blockchain technology. This will save costs, boost quality control, and raise consumer confidence that the goods they buy are genuine and high calibre. However, there is a research gap in the implications of blockchain technology in the manufacturing sector. The aim of this research was to investigate the challenges and opportunities of blockchain technologies in the manufacturing sector. In order to accomplish the study’s goal, a two-stage systematic literature review technique was used, with the PRISMA framework being used to gather pertinent data from reliable sources like Scopus. The study contained 117 research papers, which were analysed using descriptive and scientometric methods and lysis to synthesise the literature and investigate important research clusters using the centrality and co-occurrence of keywords. The study’s conclusions point to the potential of blockchain technology to support decentralised manufacturing systems that provide risk-free and trustworthy cooperation among multiple stakeholders. The report also discusses the advantages and drawbacks of using blockchain in manufacturing and offers information on recent developments in the field of digital manufacturing that are related to blockchain technology. This study emphasises the value of blockchain technology for the industrial sector and the need for more research to fully understand its potential. Blockchain technology may help the manufacturing industry become more effective, transparent, and quality assured while also reducing costs and fostering better confidence among supply chain actors.