In this work, incremental forming of pure niobium planar isotropic sheets was studied; in particular, two different types of test were conducted by varying the tool/sheet contact conditions, in order to understand the complex phenomena interesting this hard-to-form non-conventional material and to focus the attention on its formability and the finishing of the worked surfaces. From the tests, the formability limits were determined, the forming forces were acquired and analysed, the quality of the worked surfaces was evaluated with measures of roughness and high-magnification visual inspection, as well as the failures of the sheets were observed and interpreted. The results highlight that a proper choice of the contact conditions can avoid the occurrence of galling while preserving an optimal carrying out of the process. In any case, very good surface finishing and workability of niobium sheets, despite their brittle nature, is found when incrementally formed. As a consequence, incremental sheet forming of this non-conventional material can be considered a faisible way of manufacturing highly customized components.