Understanding hypothyroidism in Unani medicine

Alam, Anzar; Quamri, Mohd Aleemuddin; Sofi, Ghulamuddin; Md.Tarique, Barkati

doi:10.1016/j.joim.2019.05.006

Cited by 33 publications

(22 citation statements)

References 24 publications

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“…Insulin is used alone or in combination with oral hypoglycaemic agents [15] . Augmentation therapy with basal insulin is useful if some beta cell function remains [16] . Prior preclinical and clinical studies have reported that ingredients of Unani Formulation (Tukhm Hulba, Tabasheer, Shilajit, Maghz Khasta Jamun, and Afsanteen) may reveal anti-diabetes properties [17][18][19][20][21][22] .…”

Section: Introductionmentioning

confidence: 99%

Clinical efficacy of unani formulation in type ii diabetes-A randomized, single blind standard control clinical study

Khan¹,

Alam²,

Eqbal³

et al. 2020

Int. J. Phys. Educ. Sports Health

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Background and objectives: Diabetes mellitus is a chronic metabolic disorder characterized by persistent hyperglycaemia. It may be due to impaired insulin secretion, resistance to peripheral actions of insulin, or both. Unani system claimed for the efficacy of many anti-hyperglycaemic drugs, and all such drugs required validated on scientifically. Hence a clinical study was intended to evaluate the clinical efficacy of the Unani formulation in the management of diabetes. Methods: This trial was conducted as single blind randomized standard control, on 60 patients of type 2 diabetes with the test (n =30) and control (n=30) groups for 45 days. Test group received Unani Formulation twice daily at a dosage of 5 g powder, and control group received 500 mg tablet metformin twice a day before meal. The subjective (at 0, 15th, 30th, 45th), and objective parameters were evaluated respectively as pre-post care. Results: After treatment with Unani Formulation significant reduction was observed in subjective parameters (viz. polyuria, polydipsia, polyphagia and tiredness) in connotation of control group. In both groups the objective parameters FBS, PPBS, and HbA1c were found to be significantly reduced. The findings were statistically analysed using paired and non-paired tests. Conclusion: Based on the above observation, it is concluded that there is substantial anti-diabetic effect of the Unani Formulation without any adverse drug reaction.

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Section: Introductionmentioning

confidence: 99%

Clinical efficacy of unani formulation in type ii diabetes-A randomized, single blind standard control clinical study

Khan¹,

Alam²,

Eqbal³

et al. 2020

Int. J. Phys. Educ. Sports Health

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“…32 A combination of lifestyle changes and pharmacological therapy is required to maintain good metabolic control in diabetes and to keep the patient stable for the long term. 33,34 Hozayen WG et al, (2016) reported that, Arthrospira (spirulina) exhibits insulin-mimetic and anti-diabetic activity. 35 One other study documented that, spirulina is a rich source of fiber contents which may lead to reduced glucose absorption and possible action of peptides, and polypeptides generated by digestion of spirulina protein are responsible for it.…”

Section: Results: Baseline Characteristicsmentioning

confidence: 99%

Clinical Efficacy and Safety of ‘Oxy +’ in Type 2 Diabetes: A Pilot Study

Alam

Ahad

Quamri

et al. 2020

Int. J. Hum. Health Sci.

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Background and objectives: Diabetes is a common metabolic disorder.Type 2 diabetes accounts for the vast majority of around 92% of the population worldwide. Long term hyperglycemia leads to macro and microvascular complications. Oxy+ is a nutraceutical capsule which contains mainly Arthrospira (spirulina). Most of the diabetic people use it. Hence a clinical trial was conducted to evaluate the clinical efficacy and safety of Oxy + in Type 2 Diabetes.Material Methods: The study was designed as a single-blind pilot study; 10 eligible patients of type 2 diabetes were allocated. Oxy+ was given in capsule form; 2 capsules twice daily orally for 45 days after the meal. Test drug was evaluated on subjective parameters at 0th, 15th, 30th and 45th days whereas objective parameters were assessed before and after the treatment. The results of the intervention were analyzed using suitable statistical methods.Results and Observation:The study effects on subjective parameters like polyuria, tiredness, polyphagia, polydipsia, and Tingling Sensation were found significantly reduced. The objective parameters were assessed before and after as Mean ± SD for FBS (164.4±36.019 vs 111.1±25.075), PPBS (248.5±51.70 vs 170.1±45.148) and HbA1c (9.14±1.517 vs 6.95±1.224).The results were analyzed after using paired‘t’ test.Interpretation and Conclusion:The findings about both parameters (subjective and objective) that the ‘Oxy+’ is effective in type 2 diabetes and the cure was considerable. Safety parameters (SGOT, SGPT, Blood Urea, and Serum Creatinine) were remained unchanged. Therefore, it can be concluded that the ‘Oxy+’ would be safe and effective in the management of type 2 diabetes.International Journal of Human and Health Sciences Vol. 05 No. 01 January’21 Page: 96-100

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“…The Unani medicine system classics explicitly state that health care is superior to treatment [5,11,18]. During disease conditions, therapy is carried out using the opposite temperament nondrug (diet) and drug factors, whereas, for health maintenance, nondrug factors of the same temperament are often used [2,3]. Unani medicine puts particular emphasis on the six important factors (Asbab-e-Sitta Zarooriya) for health maintenance, i.e., ambient air, food and drink, bodily movement and repose, mental movement and repose, sleep and wakefulness, and evacuation and retention [8,11].…”

Section: Preventive Measures (Tahaffuzi Tadabeer)mentioning

confidence: 99%

“…Any disruption in the equilibrium of humours causes disease and thus the treatment seeks to restore balance by employing measures that counteract the deranged humours and temperament, etc. (preventive measures and including drugs) [2]. Furthermore, the Unani system of medicine also believes that Quwat-e-mudabbir-e-Badan (medicatrix-naturae) is the supreme force that regulates all the functions of the body and acts against the diseases [3].…”

Section: Introductionmentioning

confidence: 99%

Understanding COVID-19 in the light of epidemic disease described in Unani medicine

Alam

Quamri

Sofi

et al. 2020

Drug Metabolism and Personalized Therapy

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Unani system of medicine is based on the humoral theory postulated by Hippocrates, according to him the state of body health and disease are regulated by qualitative and quantitative equilibrium of four humours. Amraz-e-Waba is an umbrella term which is used in Unani medicine for all types of epidemics (smallpox, measles, plague, Hameer Saifi, influenza, Nipaha, Ebola, Zika, and 2019 novel coronavirus, etc.) mostly fatal in nature. The coronavirus disease 2019 (COVID-19) is a severe acute respiratory infection, and the pathogenesis and clinical features resemble with those of Nazla-e-Wabaiya (influenza) and Zatul Riya (pneumonia) which were well described many years ago in Unani text such as high-grade fever, headache, nausea and vomiting, running nose, dry cough, respiratory distress, alternate and small pulse, asthenia, foul smell from breath, insomnia, frothy stool, syncope, coldness in both upper and lower extremities, etc. The World Health Organization declared COVID-19 as a global emergency pandemic. Unani scholars like Hippocrates (370–460 BC), Galen (130–200 AD), Rhazes (865–925 AD), and Avicenna (980–1037 AD) had described four etiological factors for Amraz-e-Waba viz., change in quality of air, water, Earth, and celestial bodies, accordingly mentioned various preventive measures to be adopted during epidemics such as restriction of movement, isolation or “quarantena”, and fumigation with loban (Styrax benzoin W. G. Craib ex Hartwich.), sandalwood (Santalum album L.), Zafran (Crocus sativus L.), myrtle (Myrtus communis L.), and roses (Rosa damascena Mill.) and use of vinegar (sirka) and antidotes (Tiryaq) as prophylaxis, and avoiding consumption of milk, oil, sweet, meat, and alcohol. This review focuses and elaborates on the concept, prevention, and probable management of COVID-19 in the light of Amraz-e-Waba.

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Understanding hypothyroidism in Unani medicine

Cited by 33 publications

References 24 publications

Clinical efficacy of unani formulation in type ii diabetes-A randomized, single blind standard control clinical study

Clinical efficacy of unani formulation in type ii diabetes-A randomized, single blind standard control clinical study

Clinical Efficacy and Safety of ‘Oxy +’ in Type 2 Diabetes: A Pilot Study

Understanding COVID-19 in the light of epidemic disease described in Unani medicine

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