Rural agrarian societies, like Bangladesh, rely substantially on women as primary contributors to crop production. Their involvement covers a broad spectrum, from the first stage of seed sowing to the ultimate phase of marketing agricultural products. Information and communication technology (ICT) in agriculture could be a transformative tool for women’s agricultural involvement. Despite the inherent challenges associated with ICT adoption, it has emerged as an effective catalyst for improving the livelihoods of rural women in Bangladesh. This study investigates the impacts of ICT on the livelihoods of rural women. This study concurrently addresses the challenges that infringe upon its sustainability. The study was conducted within Oxfam Bangladesh’s ICT interventions implemented upon the women farmers in Dimla Upazila, Nilphamari, Bangladesh. We employed a mixed-methods research approach to examine the multilayered impacts of ICT on women farmers’ livelihoods. Our findings indicate that ICT support has improved the livelihoods of rural women through a comprehensive capital-building process encompassing human capital, social capital, financial capital, physical capital, and political capital, facilitated by creating an enabling environment. The study also unfolded several challenges stemming from aspects of ICT integration, including the disappearance of indigenous agroecological knowledge and the disruption of traditional multicropping practices. In light of the study’s outcomes, a key recommendation emerges, emphasizing the importance of integrating indigenous agroecological knowledge in the widescale implementation of ICT initiatives. Acknowledging and accommodating indigenous knowledge can enhance the sustainability of ICT-driven livelihood enhancements for rural women in Bangladesh.