The pandemic of The COVID-19 caused by the Severe Acute Respiratory Syndrome Coronavirus 2 (SARS-CoV-2) has changed global systems, at least temporarily. There is good evidence that the virus originated in wild animals around the Chinese city of Wuhan and spread to other areas and became a pandemic affecting almost all countries in the globe. This article explores the pandemic through a systems science approach and views it from the perspective of the SARS-CoV-2 virus. It proposes a novel conceptualization where the pandemic emerges from four converging systems: the earth systems, the urbanocene (i.e. the urbanization processes and spaces that have become the main living space of the human species), the system of mobile humans and objects, and the virus with its potential to infect. Loss of biodiversity is an important change to the earth system that promotes the emergence of zoonotic infections. The infective virus and its transmissibility are other factors promoting the epidemic. The urbanocene has resulted in high densities of populations that facilitate the spread of epidemics. Finally, the hyper-connectivity of human species and physical objects it has produced (e.g. planes and cargo) and their movement across thousands of miles often from city to city has promoted widespread dissemination of the virus. As the underlying systems evolved in parallel, a critical point was reached which resulted in synergies that led to the emergence of the COVID-19 pandemic.