“…Those difficulties encountered by students may be attributed to two main factors: the difficulty of grasping biology concepts and "working scientifically" skills, and the overloaded curriculum.Studies have reported that students face difficulties in many abstracts concepts or topics in biology, at both high schools and university levels, including the concepts of hormones, cells, genes and chromosomes, mitosis and meiosis, and the nervous system (Agboghoroma and Oyovwi, 2015, Agorram et al, 2010, Chattopadhyay, 2005and Tekkaya et al, 2001, in addition to other topics like water and gas transport in plants, protein synthesis, photosynthesis and respiration, gaseous exchange, energy, organs, physiological processes and oxygen transport (Çimers, 2012). Adding to the abstract content, the nature of science itself, which requires learning and applying "working scientifically skills" throughout the course of study, is a major problem for students.…”