Introduction: Providing dental treatment in humanitarian context has always been a challenge, as dental treatment requires a lot of tools and expensive equipment, and most of the treatment takes long time and effort to finish. This research aims to study the oral health status and the need for dental treatments among the refugees' residents in Karatepe refugee camps in Lesvos Island, Greece. And to study the relation of oral health with different demographic variable and the duration of stay inside the camp.Methods and Materials: A cross-sectional study was conducted to study the oral health status among the refugees, data was collected from the patients after obtaining informed consent to participate in the research. Data regarding demographic variables, oral health (DMFT index), medical history, and the time spend in the camp have been collected. Data was collected between May-September 2021, and the final sample size was 996 patients. SPSS V.22 was used to analyze the data using both descriptive and inferential statistics. Results: Age ranged between 2-73, and was on average 28 years, males were (61.1%), females (38.9%), and the majority of the sample were from Afghanistan (64.9%) and Syria (22.8%). Most of the reugees spent 1-2 years inside the camp (34%). The main complaint of the patients was pain (34.2%), and the main treatment provided was extraction (32.7%). Significant difference was found between age (0.032), nationality (0.002), medical history (0.001), and the time spend in the camp (0.021), however, gender didn't show significant difference (0.072). Conclusion: More attention should be given to oral health as the main complaint of the patients was pain, however, the lack of access to dental services inside the camp makes it hard to save the teeth and makes extraction the only possible solution.