Understanding splenectomy for children with hereditary spherocytosis

Rice, Henry E.

doi:10.1002/pbc.26109

Cited by 1 publication

(1 citation statement)

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“…Explanation for therapeutic result of this procedure is based on the evidence that abnormal or damaged red blood cells passing through the spleen red pulp are removed by the splenic macrophage system. However, there are concerns regarding short-and long-term risks and benefits of surgery [21]. Following these up-to-date recommendations that also existed few decades ago, in the present patient, splenectomy was performed in 2013.…”

Section: Discussionmentioning

confidence: 77%

The course and outcome of pregnancy in patient with concomitant Gilbert syndrome and hereditary spherocytosis: a unique case report

Bapayeva¹,

Terzić²,

Togyzbayeva³

et al. 2019

Clin. Exp. Obstet. Gynecol.

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Gilbert syndrome (GS) is an autosomal dominant mild unconjugated hyperbilirubinemia. Hereditary spherocytosis (HS) is an inherited condition of non-immune heterogeneous hemolytic anemia. These two diseases can be very rarely diagnosed in one patient, but there is not one case reported in pregnant patient. The authors present a unique case of concomitant both diseases in pregnancy. The patient was 25-years-old, conceived spontaneously, and carefully observed throughout the pregnancy. Considering that both diseases might have a detrimental influence on pregnancy course and outcome, especially in this case with severe form of HS, the woman was hospitalized and carefully observed until the end of pregnancy. She delivered vaginally without any feto-maternal complications. In conclusion, coexisting GS and HS during pregnancy deserve careful monitoring and up-to-date treatment. This case report shows that a contemporary approach to the pregnant patient with GS and HS can result in the delivery of a healthy baby without any complications.

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Section: Discussionmentioning

confidence: 77%