Understanding the Changing Landscape of Health Disparities in Chronic Liver Diseases and Liver Cancer

Herren, Olga M.; Gillman, Arielle S.; Marshall, Vanessa; Das, Rina

doi:10.1016/j.gastha.2022.12.001

Cited by 6 publications

(1 citation statement)

References 151 publications

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“…Differences in liver disease etiology, including presence of comorbidities[ 30 ] and genetic variant frequencies associated with increased risk [ 31 ], healthcare care access/utilization, and HCC surveillance utilization/adherence[ 27 , 32 ] likely contribute to differences in HCC severity at diagnosis. A recent and thorough discussion of liver cancer disparities in the U.S. and challenges, gaps, and opportunities for the field was recently published to discuss these differences[ 33 ].…”

Section: Discussionmentioning

confidence: 99%

Disparities in hepatocellular carcinoma incidence among Hispanic and non-Hispanic adults in Arizona: Trends between 2009-2017

Morrill,

Wightman,

Cruz

et al. 2024

Annals of Epidemiology

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Section: Discussionmentioning

confidence: 99%

Disparities in hepatocellular carcinoma incidence among Hispanic and non-Hispanic adults in Arizona: Trends between 2009-2017

Morrill,

Wightman,

Cruz

et al. 2024

Annals of Epidemiology

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Unveiling Disparities: Analyzing Hispanic Inclusion in Liver Cancer Research Databases in the United States

Figueroa,

Greten,

Bonilla

2024

J. Racial and Ethnic Health Disparities

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Primary liver cancer, including hepatocellular carcinoma and intrahepatic cholangiocarcinoma was the sixth leading cause of cancer death in the United States in 2023. Hispanic people constitute approximately 19% of the nation’s total population according to the US Census. Hispanic patients have the highest relative incidence rates of liver cancer compared to non-Hispanic Whites and non-Hispanic Blacks, a disparity frequently overlooked in cancer research. In this study, our primary objective was to analyze the potential underrepresentation of Hispanic individuals in liver cancer research databases. We identified databases that had liver cancer-specific studies and be population-based in the United States. Our search yielded 7 cancer genomic databases, which were analyzed according to incidence percentages across ethnicity and race categories. Our study included 3104 patients; ethnic data was not reported for 13.1% (n = 406) of the patients. Samples were predominantly from individuals who identified as Not Hispanic (81.0%), Hispanic individuals represented 5.9%. Race was reported as follows: non-Hispanic Whites (61.0%), Asians (22.0%), non-Hispanic Blacks (5.4%), Other (3.1%), Native American/American Indian/Alaska Native (0.4%), Pacific Islander/Native Hawaiian (0.2%) and not reported (7.9%). These findings collectively underscore significant disparities in the representation of ethnic and racial groups, particularly Hispanics. Given the present racial and ethnic demographics of the US population and the projected surge in the Hispanic population in forthcoming years, it becomes imperative to address health disparities that may worsen without efforts to enhance proper inclusion in cancer research.

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Geographic disparities in access to liver transplant for advanced cirrhosis: Time to ring the alarm!

Bajaj,

Choudhury,

Kumaran

et al. 2024

American Journal of Transplantation

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Understanding the Changing Landscape of Health Disparities in Chronic Liver Diseases and Liver Cancer

Cited by 6 publications

References 151 publications

Disparities in hepatocellular carcinoma incidence among Hispanic and non-Hispanic adults in Arizona: Trends between 2009-2017

Disparities in hepatocellular carcinoma incidence among Hispanic and non-Hispanic adults in Arizona: Trends between 2009-2017

Unveiling Disparities: Analyzing Hispanic Inclusion in Liver Cancer Research Databases in the United States

Geographic disparities in access to liver transplant for advanced cirrhosis: Time to ring the alarm!

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