Understanding the Pathways from Depression to Suicidal Risk from the Perspective of the Interpersonal–Psychological Theory of Suicide

Kang, Nan; You, Jianing; Huang, Jiyi; Ren, Yaxuan; Lin, Min Pei; Xu, Shuang

doi:10.1111/sltb.12455

Cited by 29 publications

(28 citation statements)

References 54 publications

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“…The substantial association between both IGD and suicidal ideation and psychiatric problems such as insomnia and depression may shed insights to our understanding about the mechanism. Depression is one of the strongest predictors of suicidal ideation [ 20 ]. Majority (> 90%) of people who committed suicide express depressive symptoms simultaneously, and this co-occurrence rate in adolescent suicide cases is more than 50% [ 21 ].…”

Section: Introductionmentioning

confidence: 99%

Serial multiple mediation of the association between internet gaming disorder and suicidal ideation by insomnia and depression in adolescents in Shanghai, China

Yang

Wang

et al. 2020

BMC Psychiatry

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Background High prevalence and strong relationships among suicidal ideation, Internet gaming disorder (IGD), insomnia, and depression have been reported for adolescents worldwide, but the mechanism underlying these psychological problems remains unclear. This cross-sectional study explored the mediating effect of insomnia and depression on the association between IGD and suicidal ideation. Methods Participants were 1066 adolescents (median age = 13.0 years) with Internet games exposure in the previous 12 months from junior high schools in Shanghai, China. Questionnaire measures of suicidal ideation, IGD, insomnia, depressive symptoms, and background characteristics were obtained. Path analysis was conducted to test the multiple mediating roles of insomnia and depression. Results Suicidal ideation, IGD, insomnia, and depression prevalence was 27.2, 13.6, 9.2, and 17.0%, respectively. A serial multiple mediation model was generated. The mediation effect of insomnia and depression on the pathway from IGD to suicidal ideation was 45.5% (direct effect: standardized estimate [Std. estimate] = 0.186; total indirect effect: Std. estimate = 0.155). The association between IGD and depression was partially mediated by insomnia (direct effect: Std. estimate = 0.211; indirect effect: Std. estimate = 0.135). The proposed model fit the data well. Conclusions Insomnia and depression may serially mediate the association between IGD and suicidal ideation. IGD was positively associated with insomnia, then with depression, which in turn positively contributed to suicidal ideation. We suggest greater monitoring of Internet use and prevention of insomnia and depression to mitigate the risk of suicidal ideation among Chinese adolescents.

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Section: Introductionmentioning

confidence: 99%

Serial multiple mediation of the association between internet gaming disorder and suicidal ideation by insomnia and depression in adolescents in Shanghai, China

Yang

Wang

et al. 2020

BMC Psychiatry

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“…Additionally, negative emotion was indirectly linked to a suicide attempt through both NSSI and SI. Similarly, NSSI has also been reported as a partial mediator between depression and suicidal risk, with depression also having a direct relationship to suicidal risk (Kang et al ., 2018). These studies support a ‘graduation’ hypothesis from less to more severe experiences.…”

Section: Discussionmentioning

confidence: 99%

Negative self-evaluation and the genesis of internal threat: beyond a continuum of suicidal thought and behaviour

Butter¹,

Shevlin²,

Murphy³

2018

Psychol. Med.

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BackgroundDeath by suicide is often preceded by attempted suicide, suicidal ideation and non-suicidal self-injury. These extreme thoughts and behaviours have been considered in terms of a continuum of suicidality. Little known research, however, has considered a suicide continuum that extends beyond these extreme thoughts and behaviours and incorporates a much wider array of phenomena that may vary in severity and may constitute a broader negative self-evaluation (NSE) continuum.MethodHarvesting key indicators of NSE from a British epidemiological survey (N = 8580), the current study used exploratory factor analysis, confirmatory factor analysis and factor mixture modelling to (i) identify the dimensional structure of NSE in the general population and (ii) profile the distribution of the resultant NSE dimensions. Multinomial logistic regression was then used to differentiate between classes using an array of risk variables, psychopathology outcome variables and a suicide attempt indicator.ResultsA 4-factor model that reflected graded levels of NSE was identified; (F1) Low self-worth & subordination (F2) depression, (F3) suicidal thoughts, (F4) self-harm (SH). Seven classes suggested a clear pattern of NSE severity. Classes characterised by higher levels across the dimensions exhibited greater risk and poorer outcomes. The greatest risk for suicide attempt was associated with a class characterised by engagement in SH behaviour.ConclusionsLow self-worth, subordination and depression, while representative of distinct groups in the population are also highly prevalent in those who entertain suicidal thoughts and engage in SH behaviour. The findings promote further investigation into the genesis and evolution of suicidality and internal threat.

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“…Moreover, rather than focusing on their suicidal ideation only, awareness of the relationships of different physical disorders with depression would help identify patients at a high SA risk, thereby preventing suicidal death. However, depression mediates the relationship between value strain, deprivation strain, aspiration strain, coping strain, and suicidality (8). Psychological strain may cause suicidal behaviors or impulsive suicide in patients with a lack of social support/ coping capacities (20), poor functional status (21,22), and disorders of subjective perception including anxiety, panic, or other mental disorders (23,24).…”

Section: And 712 Permentioning

confidence: 99%

“…Depression is a well-established predictor of suicidal behaviors (7,8). Researchers have investigated interactions between suicidality and medical conditions for years; however, only few researchers have conducted population-based studies on this topic (9,10).…”

Section: Introductionmentioning

confidence: 99%

Suicide Attempt and Suicidal Drug Overdose in Chronic Obstructive Pulmonary Disease Patients With or Without Depression

Lin¹,

Harnod

Lin

et al. 2020

Front. Psychiatry

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Background: To determine differences in the incidence and risks of suicide attempt (SA) and suicidal drug overdose (SDO) between chronic obstructive pulmonary disease (COPD) patients with and without comorbid depression by using data from Taiwan's National Health Insurance Research Database. Methods: We analyzed the data of patients aged ≥20 years who had received a COPD diagnosis between 2000 and 2012. These COPD patients were divided into those with and without depression, and they were compared against a cohort from the general population. We calculated adjusted hazard ratios and the corresponding 95% confidence intervals for SA and SDO in the three cohorts after adjustment for age, sex, and comorbidities. Results: Until the end of 2012, 5.81% of patients with COPD developed depression. The incidence of SA and SDO in COPD patients with and without depression was 29.7 and 4.69 per 10,000 person-years and 71.2 and 20.9 per 10,000 person-years, respectively. COPD patients with depression had 13.6-and 10.0-fold higher risks of SA and SDO, respectively, than did controls. Particularly, an increased risk of SA caused by the enhancement effects of depression on COPD was noted in patients aged less than 50 years. Conclusion: SA and SDO risks are extremely high in Taiwanese COPD patients with depression. Our findings suggest that clinicians should be aware that for COPD patients with comorbid depression, prescribing a large amount of medications may be associated with SA risk through SDO.

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Understanding the Pathways from Depression to Suicidal Risk from the Perspective of the Interpersonal–Psychological Theory of Suicide

Cited by 29 publications

References 54 publications

Serial multiple mediation of the association between internet gaming disorder and suicidal ideation by insomnia and depression in adolescents in Shanghai, China

Serial multiple mediation of the association between internet gaming disorder and suicidal ideation by insomnia and depression in adolescents in Shanghai, China

Negative self-evaluation and the genesis of internal threat: beyond a continuum of suicidal thought and behaviour

Suicide Attempt and Suicidal Drug Overdose in Chronic Obstructive Pulmonary Disease Patients With or Without Depression

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