2021
DOI: 10.3390/ijerph182212130
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Understanding the Relationship between Depression and Chronic Diseases Such as Diabetes and Hypertension: A Grounded Theory Study

Abstract: There is a bi-directional relationship between depression and chronic illnesses such as diabetes and hypertension. This comorbidity is associated with higher mortality risk and diminishes the efficacy of interventions. The specific mechanisms of this mutual influence are still not fully understood, and most intervention protocols address these conditions separately. This study aims to improve our understanding of this relationship. We interviewed 18 patients and 24 health care professionals, focusing on unders… Show more

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Cited by 37 publications
(16 citation statements)
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“…Therefore, in comparison to these prevalence estimates in older Chinese adults in both community and primary care settings, we found the higher risk of depressive disorders and their subtypes in Chinese patients with hypertension. In the literature, possible explanations for how hypertension results in or exacerbates depression include the mental health burden of suffering from hypertension and its negative impact on a person’s quality of life, a low sense of self-worth, low self-esteem, and a loss of locus of control due to the negative psychological effect of hypertension, and structural changes in brain areas related to emotion as a result of pathophysiologic effects of hypertension on central nervous system ( 42 ).…”
Section: Discussionmentioning
confidence: 99%
“…Therefore, in comparison to these prevalence estimates in older Chinese adults in both community and primary care settings, we found the higher risk of depressive disorders and their subtypes in Chinese patients with hypertension. In the literature, possible explanations for how hypertension results in or exacerbates depression include the mental health burden of suffering from hypertension and its negative impact on a person’s quality of life, a low sense of self-worth, low self-esteem, and a loss of locus of control due to the negative psychological effect of hypertension, and structural changes in brain areas related to emotion as a result of pathophysiologic effects of hypertension on central nervous system ( 42 ).…”
Section: Discussionmentioning
confidence: 99%
“…Further, chronic stress left unnoticed can suppress the immune system, inviting a group of chronic health conditions (Salleh, 2008). It is evident from the literature that there is a bidirectional association between psychological disturbances such as depression, anxiety, mood disorders, and various health issues (Herrera et al ., 2021; Bobo et al ., 2022). It appears like a loop where the diagnosis of chronic health conditions promotes psychological disturbances such as depression (Ma et al ., 2021), which leads to poor prognosis and rapid progression of the condition (Simon, 2001).…”
Section: Psychosocial and Cultural Determinants Of Health And The Pro...mentioning
confidence: 99%
“…Another possible causative factor is that there is no target organ damage and there are no typical symptoms of hypertension, making people with hypertension ignore their hypertension problems (Kalehoff & Oparil, 2020;Obrycki et al, 2020). Boredom related to hypertension management, which is a long-term therapy, is also one of the causative factors that cannot be denied (Herrera et al, 2021).…”
Section: The Relationship Between Age and Adherence And Barriers To M...mentioning
confidence: 99%