Understanding the use of oral rehydration therapy: A narrative review from clinical practice to main recommendations

Aghsaeifard, Ziba; Heidari, Ghobad; Alizadeh, Reza

doi:10.1002/hsr2.827

Cited by 13 publications

(6 citation statements)

References 43 publications

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“…One pivotal aspect of managing dehydration resulting from diarrhea in children is effective rehydration through the administration of ORS. This simple yet highly effective intervention has the potential to save lives, especially in resource-limited settings 7 . However, the widespread adoption of this rehydration strategy by mothers for their children hinges significantly on their level of knowledge regarding the preparation and proper usage of ORS 10 .…”

Section: Discussionmentioning

confidence: 99%

“…World Health Organization and experts universally recommend a specific approach when dealing with mild to moderate dehydration in children, emphasizing the utilization of commercially prepared oral rehydration solutions (ORS) 7 . The rationale behind this recommendation is multifaceted.…”

Section: Introductionmentioning

confidence: 99%

“…However, ORS holds the additional advantages of cost-effectiveness and a lower incidence of adverse effects, making it a preferred choice in many clinical settings. This dual effectiveness, coupled with its safety profile and economic feasibility, positions ORS as a cornerstone in the management of dehydration associated with acute diarrhea, particularly in pediatric populations 7 .…”

Section: Introductionmentioning

confidence: 99%

“…Various studies have pointed out that mothers had poor knowledge of the etiology of the disease, symptoms, treatment, and methods to handle diarrheal children [7][8][9] . Since diarrhea causes childhood mortality more frequently around the globe, specifically in underdeveloped countries like Pakistan, extraordinary improvements in the knowledge of caretakers regarding the management and treatment of diarrhea are needed.…”

Section: Introductionmentioning

confidence: 99%

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Knowledge of Caretakers about the Use of Oral Rehydration Solutions in Children with Acute Diarrhea

2023

PJMD

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Background: Diarrhea is known to be the major factor causing morbidity and mortality, especially among pediatric age groups globally. This study was done to assess the knowledge of caretakers regarding the use of oral rehydration solution (ORS) in children with acute diarrhea. Methods: This cross-sectional study was conducted at the Department of Pediatric Medicine, Children’s Hospital and Institute of Child Health, Multan, Pakistan, from February 2023 to July 2023. We analyzed caretakers of children aged 1-12 years who presented with acute diarrhea that had less than 14 days of duration. Both male and female caretakers, with ages ranging from 25 to 50 years, were included. Knowledge of the formulation of ORS, the process of its preparation, and usage were asked. Participants describing all correct answers about the formulation, preparation, and use of ORS were considered as having knowledge of ORS. Effect modifiers were stratiﬁed, and applying the post-stratification chi-square test, their effects on outcome were observed. A p-value≤0.05 was considered significant. Results: In a total of 240 study participants, the mean age of caretakers was 36.01±8.08 years. There were 23 (9.6%) male and 217 (90.4%) female caretakers. Among caretakers, 79 (32.9%) had knowledge of ORS while 161 (67.1%) did not know ORS. A statistically significant association of knowledge about ORS was found with residential status (p<0.001), socio-economic status (p<0.001), and source of drinking water (p<0.001). Conclusion: This study found that among caretakers of children having acute diarrhea, there was a lack of knowledge regarding ORS use, formulation, and preparation.

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Section: Discussionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Knowledge of Caretakers about the Use of Oral Rehydration Solutions in Children with Acute Diarrhea

2023

PJMD

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“…According to a UNICEF monograph from 2009, the overall utilization of ORS was reported to be only 33% in developing countries. This statistic raises concerns about the potential for increased child mortality resulting from diarrhea in areas where ORS adoption remains limited [17].…”

Section: The Role Of Immediate Fluid Resuscitation In Managing Childr...mentioning

confidence: 99%

Role of Fluid Resuscitation and Supportive Management of Diarrhea

Habib

2023

AJPR

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The pediatric population is sensitive in every aspect. There are several parts of their bodies that need extreme levels of care and support until these children have reached a mature age. Similarly, there are several aspects of health that require immediate and urgent intervention, particularly in the pediatric population for better care and management. The reason behind this is the delicate and sensitive nature of the children’s health. Compromising any aspect of pediatric care might lead to severe consequences, which could be life-threatening too. Therefore, it is in the best interest of both the parents of the children and the physicians to be vigilant about the affected children’s symptoms just so they do not miss out on any important signs that could be transient or short-lived. Diarrhea is among the pediatric conditions that can very easily take a turn for the worse if it is not managed appropriately. Diarrhea can lead to severe consequences, including death in children, especially the malnourished ones. Diarrhea results in the excessive excretion of water, and electrolytes including sodium, potassium, bicarbonate, and zinc through watery stools. Dehydration ensues when these losses are not sufficiently replenished, leading to deficits in both water and electrolytes. The extent of dehydration is categorized based on symptoms and signs that mirror the quantity of fluid expelled. Depending upon these extents and degrees of dehydration, performing immediate resuscitation measures might be necessary. Among these measures, oral rehydration therapy is considered to be one of the most useful ones. It helps replenish the electrolytes rapidly and without causing any life-threatening consequences, especially when done within the specified time. On the brighter side, these fluid resuscitative measures might be the only interventions required to stop the child's progression further towards a severe form of the disease. This review is based on this fact only, and it revolves around the importance of performing fluid resuscitation and other elementary-level supportive measures that might be the only shot at saving the life of the child if done at an early stage. Thai review will help take action under the right circumstances if such a case arises in the clinical setting.

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