In the context of Indigenous Australia, cumulative impact assessment (CIA) is a nascent field both in terms of state and territory regulation and in practice. Likewise, relative to the science of environmental and social impact assessment (ESIA), this nomenclature of CIA is recent, and its application to Indigenous interests even more so. This paper briefly reviews the available literature -internationally and within Australia -on CIA, Indigenous peoples and the extractives sector. In the Australian context, the limited CIA literature reveals a focus on the impacts to Indigenous tangible cultural heritage. The issue of cumulative impacts to Indigenous cultural landscapes is especially heightened in mining regions, and came to the attention of the wider public in relation to the Juukan Gorge site destruction in May 2020 in the Pilbara mining region. The subsequent parliamentary inquiry and 172 submissions served to focus attention on the cumulative impacts of the industry across both space and time for the impacted Indigenous customary landholders. This paper condenses the findings from a specific component of a larger project entitled 'Towards a Framework for Regional Cumulative Impact Assessment', under the auspices of the Cooperative Research Centre for Transformations in Mining Economies (CRC TiME). As the focus is on application and informing industry and regulators, this focus on Indigenous CIA also reviewed current Australian practice and methods, finding that there has not been a specific methodology developed for Indigenous CIA in relation to the extractives sector. There are, however, a range of methodologies that are more useful and relevant than others, as they begin to address Indigenous-specific interests. A fundamental element in developing an effective Indigenous CIA method is to ensure that it is able to identify what the specific interests are in terms of 'values' and 'significance'. This can only be done in collaboration with the Indigenous groups and knowledge holders, and requires qualitative and quantitative methods. The question of the relationship between mine closure and cumulative impacts for affected Indigenous groups will also be briefly explored, with the caveat that there are few examples of large-scale mines relinquished back to the Indigenous estate -indeed, none that this author is aware of. Nevertheless, many of the conceptual and practical aspects of CIA are heightened in closure -with additional risks and opportunities. This consideration of closure and the interface with Indigenous CIA in this paper builds upon the CRC TiME research.